ArticleScientific reports2015
Malaria Diagnosis Using a Mobile Phone Polarized Microscope.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
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Who cites it
48 citing papers in PubMed, 213 citations in OpenAlex.
- Magneto-optical microscopy platform for quantitative imaging of hemozoin in blood for malaria diagnosis.Biomedical optics express · 2026Article
- NTDscope: A multi-contrast portable microscope for disease diagnosis.PLOS global public health · 2026Article
- Deep-learning enabled rapid and low-cost detection of microplastics in consumer products following on-site extraction and image processing.RSC advances · 2025Article
- Advances in Portable Optical Microscopy Using Cloud Technologies and Artificial Intelligence for Medical Applications.Sensors (Basel, Switzerland) · 2024Review
- Development of a low-cost robotized 3D-prototype for automated optical microscopy diagnosis: An open-source system.PloS one · 2024Article
- AIDMAN: An AI-based object detection system for malaria diagnosis from smartphone thin-blood-smear images.Patterns (New York, N.Y.) · 2023Article
- Smartphone-based platforms implementing microfluidic detection with image-based artificial intelligence.Nature communications · 2023Review
- Efficient Malaria Parasite Detection From Diverse Images of Thick Blood Smears for Cross-Regional Model Accuracy.IEEE open journal of engineering in medicine and biology · 2023Article
- Malaria Detection Accelerated: Combing a High-Throughput NanoZoomer Platform with a ParasiteMacro Algorithm.Pathogens (Basel, Switzerland) · 2022Article
- Microscopic Imaging Methods for Organ-on-a-Chip Platforms.Micromachines · 2022Review
- Advances and challenges in automated malaria diagnosis using digital microscopy imaging with artificial intelligence tools: A review.Frontiers in microbiology · 2022Review
- Computational Methods for Automated Analysis of Malaria Parasite Using Blood Smear Images: Recent Advances.Computational intelligence and neuroscience · 2022Review
- Innovations in3 Biotech · 2021Review
- Machine learning and applications in microbiology.FEMS microbiology reviews · 2021Review
- Automated phenotyping of mosquito larvae enables high-throughput screening for novel larvicides and offers potential for smartphone-based detection of larval insecticide resistance.PLoS neglected tropical diseases · 2021Article
- Smartphone-based optical spectroscopic platforms for biomedical applications: a review [Invited].Biomedical optics express · 2021Review
- Lensless, reflection-based dark-field microscopy (RDFM) on a CMOS chip.Biomedical optics express · 2020Article
- Lidar reveals activity anomaly of malaria vectors during pan-African eclipse.Science advances · 2020Article
- Cell phone digital microscopy using an oil droplet.Biomedical optics express · 2020Article
- Portable bright-field, fluorescence, and cross-polarized microscope toward point-of-care imaging diagnostics.Journal of biomedical optics · 2019Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Malaria remains a major global health burden, and new methods for low-cost, high-sensitivity, diagnosis are essential, particularly in remote areas with low-resource around the world. In this paper, a cost effective, optical cell-phone based transmission polarized light microscope system is presented for imaging the malaria pigment known as hemozoin. It can be difficult to determine the presence of the pigment from background and other artifacts, even for skilled microscopy technicians. The pigment is much easier to observe using polarized light microscopy. However, implementation of polarized light microscopy lacks widespread adoption because the existing commercial devices have complicated designs, require sophisticated maintenance, tend to be bulky, can be expensive, and would require re-training for existing microscopy technicians. To this end, a high fidelity and high optical resolution cell-phone based polarized light microscopy system is presented which is comparable to larger bench-top polarized microscopy systems but at much lower cost and complexity. The detection of malaria in fixed and stained blood smears is presented using both, a conventional polarized microscope and our cell-phone based system. The cell-phone based polarimetric microscopy design shows the potential to have both the resolution and specificity to detect malaria in a low-cost, easy-to-use, modular platform.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.