ArticleSurgery today2016
Intraoperative blood loss is not a predictor of prognosis for pancreatic cancer.
Article in Surgery today, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 23 citations in OpenAlex.
- Effects of surgical trauma and intraoperative blood loss on tumour progression.Frontiers in oncology · 2024Review
- ASO Author Reflections: OGT-Assisted Method Made the Overlap Esophagojejunostomy in Laparoscopic Total Gastrectomy Easier.Annals of surgical oncology · 2023Article
- Clinicopathological significance of MYL9 expression in pancreatic ductal adenocarcinoma.Cancer reports (Hoboken, N.J.) · 2022Article
- Article
- Details and Outcomes of Distal Pancreatectomy with Celiac Axis Resection Preserving the Left Gastric Arterial Flow.Annals of surgical oncology · 2021Article
- Exposure to Blood Components and Inflammation Contribute to Pancreatic Cancer Progression.Annals of surgical oncology · 2021Article
- Perioperative Glucocorticoids are Associated with Improved Recurrence-Free Survival After Pancreatic Cancer Surgery: A Retrospective Cohort Study with Propensity Score-Matching.Therapeutics and clinical risk management · 2021Article
- A robust 6-mRNA signature for prognosis prediction of pancreatic ductal adenocarcinoma.International journal of biological sciences · 2019Article
- Reproducibility of preoperative endoscopic injection of botulinum toxin into the sphincter of Oddi to prevent postoperative pancreatic fistula.Innovative surgical sciences · 2018Article
- A novel messenger RNA signature as a prognostic biomarker for predicting relapse in pancreatic ductal adenocarcinoma.Oncotarget · 2017Article
- Significance of lymph node metastasis in pancreatic neuroendocrine tumor.Surgery today · 2017Article
- Safety and efficacy of postoperative pharmacologic thromboprophylaxis with enoxaparin after pancreatic surgery.Surgery today · 2017Article
- Necessity for autologous blood storage and transfusion in patients undergoing pancreatoduodenectomy.Surgery today · 2017Article
- Attempts to prevent postoperative pancreatic fistula after distal pancreatectomy.Surgery today · 2017Review
- The impact of margin status determined by the one-millimeter rule on tumor recurrence and survival following pancreaticoduodenectomy for pancreatic ductal adenocarcinoma.Surgery today · 2017Article
- MicroRNA-155 Controls Exosome Synthesis and Promotes Gemcitabine Resistance in Pancreatic Ductal Adenocarcinoma.Scientific reports · 2017Article
- A comparative study on the complications of conventional and end-to-side inserting pancreatojejunostomy after pancreaticoduodenectomy.Surgery today · 2017Article
- Impact of Intraoperative Blood Loss on the Survival of Patients With Stage II/III Colorectal Cancer: A Multicenter Retrospective Study.In vivo (Athens, Greece)Article
- The Impact of Intraoperative Blood Loss on the Survival of Patients With Stage II/III Pancreatic Cancer.In vivo (Athens, Greece)Article
Corrections and comments
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Authors and funding
12 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe relationship between intraoperative blood loss (IBL) and prognosis has been reported for some types of cancer, but not for pancreatic cancer, which has one of the highest mortality rates of any cancer. We conducted this study to analyze the relationship between IBL and clinical outcome for patients undergoing radical surgery for pancreatic cancer.
methodsThe subjects of this study were 144 patients who underwent curative pancreatectomy for invasive pancreatic cancer between 2002 and 2014. Clinicopathological characteristics were recorded and prognostic factors were identified by univariate and multivariate analyses.
resultsLarge IBL was significantly associated with advanced tumor stage, a long operation time, a large tumor, portal vein resection, and blood transfusion. According to univariate analysis, IBL was also significantly associated with overall survival (OS) and relapse-free survival (RFS); however, it was not an independent prognostic factor for OS and RFS in multivariate analysis. According to multivariate analysis, lymph node metastasis and R-status were independent prognostic factors for OS and RFS. A subgroup analysis of patients who received no blood transfusion showed similar results.
conclusionMinimizing IBL is very important; however, the present study found that positive lymph node metastasis and R-status were stronger independent prognostic factors for pancreatic cancer.
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