Evidence map›Paper›PMID 26302727›Full record

ArticleAllergy & rhinology (Providence, R.I.)2015

Commentary on gender differences in prevalence, treatment, and quality of life of patients with chronic rhinosinusitis.

Elisabeth H Ference, Bruce K Tan, Kathryn E Hulse, Rakesh K Chandra, Sean B Smith, Robert C Kern, David B Conley, Stephanie Shintani Smith

Open access · goldAbstract read
In one paragraph

Article in Allergy & rhinology (Providence, R.I.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 91 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Sexual Dimorphism in Allergic and Mast Cell-Associated Diseases.Clinical reviews in allergy & immunology · 2026
    Review
  5. Article
  6. Effects of urban PM2.5 on primary sinonasal epithelial cells in individuals with chronic rhinosinusitis.Toxicological sciences : an official journal of the Society of Toxicology · 2026
    Article
  7. Biological Sex and Chronic Rhinosinusitis Diagnosis and Biomarkers.JAMA otolaryngology-- head & neck surgery · 2026
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Observational
  17. Article
  18. Article
  19. Normative data for interpreting the SNOT-22.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Elisabeth H FerenceDepartment of Otolaryngology - Head and Neck Surgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois,, USA.
Bruce K Tan
Kathryn E Hulse
Rakesh K Chandra
Sean B Smith
Robert C Kern
David B Conley
Stephanie Shintani Smith
Northwestern University · USVanderbilt University · US

Funding

Training Program In Lung SciencesT32HL076139 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KAREN M RIDGE, Jacob I Sznajder · 2004 to 2026
$9.6M
Systems Genetics Approach to Gene Discovery in Chronic RhinosinusitisU19AI106683 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SCHLEIMER, ROBERT P · 2014 to 2017
$7.9M
Career Development in Women's Health (CDWH)K12HD055884 · NICHD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI DUNAIF, ANDREA E · 2007 to 2016
$4.2M
Role for B-cell mediated olfactory loss in Chronic Sinusitis with Nasal PolypsK23DC012067 · NIDCD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI TAN, BRUCE K · 2012 to 2016
$1.1M
AHRQ HHS T32 HS000078NHLBI NIH HHS T32 HL076139NIAID NIH HHS U19 AI106683NICHD NIH HHS K12 HD055884NIDCD NIH HHS K23 DC012067
6 · The paper itself

Abstract

objectiveTo examine the existing evidence on gender differences in the prevalence, treatment, and quality of life of patients with chronic rhinosinusitis (CRS).

methodsReview of the literature and expert opinion.

resultsFrom a sociologic standpoint, women have historically been considered more likely to report symptoms, seek medical care, and give poorer self-evaluation of health, which may bias data toward increased prevalence and a greater effect of CRS on quality of life in women. However, the influence of gender seems to be restricted primarily to the evaluation of general quality of life, whereas the disease-specific health-related quality of life is not different between genders. Furthermore, migraine headaches, which are more common among women, may be misdiagnosed as CRS, which contributes to gender differences in the prevalence of CRS. The degree to which reported differences in prevalence and health utilization represent biologic or physiologic differences between genders is not known; however, differences in anatomic size, tobacco susceptibility, and hormonal factors have been speculated to increase the overall susceptibility to CRS in women compared with men.

conclusionsFocused research that examines the effect of gender on the development, treatment, and outcomes of CRS is warranted.

Identifiers

PMID26302727
PMCPMC4541639
OpenAlexW1198959406

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.