ReviewZhongguo fei ai za zhi = Chinese journal of lung cancer2015
[Research Progress of Mechanisms on Intracranial Metastasis of Non-small Cell Lung Cancer after Clinical Benefit from EGFR-TKI].
Review in Zhongguo fei ai za zhi = Chinese journal of lung cancer, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
Currently epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) is widely used for treatment of non-small cell lung cancer (NSCLC) patients with EGFR mutation. However, intracranial metastasis and progression could happen to some patients while their primary tumors in lung stabilize or even shrink after EGFR-TKI treatment. And mechanisms on this phenomenon remain unclear. Recently, increasing studies have demonstrated that it is associated with the pharmacokinetics of EGFR-TKI, heterogeneity between primary tumors and metastases, EGFR mutation status and prolonged survival. Therefore, we write this review to discuss the mechanisms on intracranial metastasis of NSCLC after clinical benefit from EGFR-TKI.
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