Evidence map›Paper›PMID 26302176›Full record

ArticleExperimental and molecular pathology2015

Finding mouse models of human lymphomas and leukemia's using the Jackson laboratory mouse tumor biology database.

Dale A Begley, John P Sundberg, Debra M Krupke, Steven B Neuhauser, Carol J Bult, Janan T Eppig, Herbert C Morse, Jerrold M Ward

Abstract read
In one paragraph

Article in Experimental and molecular pathology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dale A BegleyThe Jackson Laboratory, Bar Harbor, ME USA. Electronic address: dale.begley@jax.org.
John P SundbergThe Jackson Laboratory, Bar Harbor, ME USA.
Debra M KrupkeThe Jackson Laboratory, Bar Harbor, ME USA.
Steven B NeuhauserThe Jackson Laboratory, Bar Harbor, ME USA.
Carol J BultThe Jackson Laboratory, Bar Harbor, ME USA.
Janan T EppigThe Jackson Laboratory, Bar Harbor, ME USA.
Herbert C MorseVirology and Cellular Immunology Section, Laboratory of Immunogenetics, NIAID, NIH, Bethesda, MD USA.
Jerrold M WardGlobal VetPathology, Montgomery Village, MD USA.

Funding

Shared Resource ManagementP30CA034196 · NCI · JACKSON LABORATORY · PI William Carl Skarnes · 1985 to 2026
$61.9M
Mouse Models of Human Cancer DatabaseR01CA089713 · NCI · JACKSON LABORATORY · PI BULT, CAROL J · 2002 to 2025
$17.5M
Molecular Regulation of B-Cell Differentiation and FunctionZIAAI001024 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI MORSE, HERBERT · 2009 to 2018
$8.3M
Lymphomas And Retroviral PathogenesisZIAAI000858 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI MORSE, HERBERT · 2009 to 2018
$5.3M
Intramural NIH HHSNCI NIH HHS CA034196NCI NIH HHS CA089713NCI NIH HHS P30 CA034196NCI NIH HHS R01 CA089713
6 · The paper itself

Abstract

Many mouse models have been created to study hematopoietic cancer types. There are over thirty hematopoietic tumor types and subtypes, both human and mouse, with various origins, characteristics and clinical prognoses. Determining the specific type of hematopoietic lesion produced in a mouse model and identifying mouse models that correspond to the human subtypes of these lesions has been a continuing challenge for the scientific community. The Mouse Tumor Biology Database (MTB; http://tumor.informatics.jax.org) is designed to facilitate use of mouse models of human cancer by providing detailed histopathologic and molecular information on lymphoma subtypes, including expertly annotated, on line, whole slide scans, and providing a repository for storing information on and querying these data for specific lymphoma models.

Indexed as

AnimalsDatabases, FactualDisease Models, AnimalHumansLeukemiaLymphomaMiceNeoplasms, ExperimentalDigital slidesLeukemiaLymphomaMiceMouse tumor biology databaseVirtual slides

Identifiers

PMID26302176
PMCPMC4679566

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.