Evidence map›Paper›PMID 26302085›Full record

ArticlePloS one2015

Sentiment Measured in Hospital Discharge Notes Is Associated with Readmission and Mortality Risk: An Electronic Health Record Study.

Thomas H McCoy, Victor M Castro, Andrew Cagan, Ashlee M Roberson, Isaac S Kohane, Roy H Perlis

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 1 pooled it
8.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 1 synthesis or guideline pooled it, 96 citations in OpenAlex.

  1. Pooled it
  2. Observational
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  10. Observational
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  12. Caregivers Attitude Detection From Clinical Notes.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Thomas H McCoyCenter for Experimental Drugs and Diagnostics, Department of Psychiatry and Center for Human Genetic Research, Massachusetts General Hospital, 185 Cambridge St, 6th Floor, Boston, MA 02114, United States of America.
Victor M CastroCenter for Experimental Drugs and Diagnostics, Department of Psychiatry and Center for Human Genetic Research, Massachusetts General Hospital, 185 Cambridge St, 6th Floor, Boston, MA 02114, United States of America; Partners Research Computing, Partners HealthCare System, One Constitution Center, Boston, MA 02129, United States of America.
Andrew CaganCenter for Experimental Drugs and Diagnostics, Department of Psychiatry and Center for Human Genetic Research, Massachusetts General Hospital, 185 Cambridge St, 6th Floor, Boston, MA 02114, United States of America; Partners Research Computing, Partners HealthCare System, One Constitution Center, Boston, MA 02129, United States of America.
Ashlee M RobersonCenter for Experimental Drugs and Diagnostics, Department of Psychiatry and Center for Human Genetic Research, Massachusetts General Hospital, 185 Cambridge St, 6th Floor, Boston, MA 02114, United States of America.
Isaac S KohaneDepartment of Medicine, Brigham and Women's Hospital, Suite 255, New Research Building, 77 Avenue Louis Pasteur, Boston, MA 02115, United States of America.
Roy H PerlisCenter for Experimental Drugs and Diagnostics, Department of Psychiatry and Center for Human Genetic Research, Massachusetts General Hospital, 185 Cambridge St, 6th Floor, Boston, MA 02114, United States of America.
Massachusetts General Hospital · USBrigham and Women's Hospital · USMass General Brigham · US

Funding

Research ProjectP50MH106933 · NIMH · HARVARD MEDICAL SCHOOL · PI KOHANE, ISAAC S. · 2014 to 2018
$17.0M
Fostering Research Mentorship & Training during Psychiatry Residency SupplementR25MH094612 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI FAVA, MAURIZIO, GREENFIELD, SHELLY F. · 2011 to 2022
$2.3M
NIMH NIH HHS 1P50MH106933NIMH NIH HHS P50 MH106933NIMH NIH HHS R25 MH094612
6 · The paper itself

Abstract

Natural language processing tools allow the characterization of sentiment--that is, terms expressing positive and negative emotion--in text. Applying such tools to electronic health records may provide insight into meaningful patient or clinician features not captured in coded data alone. We performed sentiment analysis on 2,484 hospital discharge notes for 2,010 individuals from a psychiatric inpatient unit, as well as 20,859 hospital discharges for 15,011 individuals from general medical units, in a large New England health system between January 2011 and 2014. The primary measures of sentiment captured intensity of subjective positive or negative sentiment expressed in the discharge notes. Mean scores were contrasted between sociodemographic and clinical groups in mixed effects regression models. Discharge note sentiment was then examined for association with risk for readmission in Cox regression models. Discharge notes for individuals with greater medical comorbidity were modestly but significantly lower in positive sentiment among both psychiatric and general medical cohorts (p<0.001 in each). Greater positive sentiment at discharge was associated with significantly decreased risk of hospital readmission in each cohort (~12% decrease per standard deviation above the mean). Automated characterization of discharge notes in terms of sentiment identifies differences between sociodemographic groups, as well as in clinical outcomes, and is not explained by differences in diagnosis. Clinician sentiment merits investigation to understand why and how it reflects or impacts outcomes.

Indexed as

Electronic Health RecordsEmotionsMortalityPatient ReadmissionEthnicityFemaleHospitalsHumansInsuranceLength of StayMaleNatural Language ProcessingPatient DischargePhysicians

Identifiers

PMID26302085
PMCPMC4547711
OpenAlexW1902025218

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.