Trial reportPloS one2015
Active Video Game Exercise Training Improves the Clinical Control of Asthma in Children: Randomized Controlled Trial.
Trial report in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01438294 (Effects of Exercise Training on Markers of Lung Inflammation and Clinical Crontrol in Asthma Children), which is not on this map. Cited by 22 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Exercise Training on Markers of Lung Inflammation and Clinical Crontrol in Asthma Children
Who cites it
22 citing papers in PubMed, 5 syntheses or guidelines pooled it, 52 citations in OpenAlex.
- Comprehensive exercise recommendations for pediatric asthma: an evidence synthesis.World journal of pediatrics : WJP · 2026Pooled it
- Efficacy of non-pharmacological interventions for childhood asthma: a systematic review and network meta-analysis.BMC pediatrics · 2025Pooled it
- Effectiveness of Video Games as Physical Treatment in Patients with Cystic Fibrosis: Systematic Review.Sensors (Basel, Switzerland) · 2022Pooled it
- Active Video Games as a Training Tool for Individuals With Chronic Respiratory Diseases: A SYSTEMATIC REVIEW.Journal of cardiopulmonary rehabilitation and prevention · 2019Pooled it
- Effects of physical exercise training on nocturnal symptoms in asthma: Systematic review.PloS one · 2018Pooled it
- Active video gaming in primary ciliary dyskinesia: a randomized controlled trial.European journal of pediatrics · 2022Trial
- Efficacy of synergistic nursing and flexible play-based approach in children with Bronchial Asthma.Pakistan journal of medical sciences · 2025Article
- Barriers to physical activity among adolescents with asthma and obesity: a qualitative study of multiple stakeholders.BMC public health · 2025Article
- Multicomponent intervention for schoolchildren with asthma: Pilot cluster randomized controlled trial.The journal of allergy and clinical immunology. Global · 2025Article
- Virtual Reality and Videogaming in Pulmonary Rehabilitation for Asthma: A Systematic Review of Clinical Outcomes and Engagement.Journal of multidisciplinary healthcare · 2025Review
- Influence of parental anxiety and beliefs about medicines on feeding and exercise in children living with asthma.Journal of child health care : for professionals working with children in the hospital and community · 2024Article
- Digital Serious Games to Promote Behavior Change in Children With Chronic Diseases: Scoping Review and Development of a Self-Management Learning Framework.Journal of medical Internet research · 2024Article
- Promoting Exercise Training Remotely.Life (Basel, Switzerland) · 2022Review
- Exergaming During Ramadan Intermittent Fasting Improve Body Composition as Well as Physiological and Psychological Responses to Physical Exercise in Adolescents With Obesity.Frontiers in nutrition · 2022Article
- COVID-19 Pandemic and Reduced Physical Activity: Is There an Impact on Healthy and Asthmatic Children?Frontiers in pediatrics · 2021Review
- A systematic review and meta-analysis of the effectiveness of virtual reality as an exercise intervention for individuals with a respiratory condition.Advances in simulation (London, England) · 2020Article
- Effects of continuous aerobic exercise on lung function and quality of life with asthma: a systematic review and meta-analysis.Journal of thoracic disease · 2020Article
- Heart rate agreement between the 20-meter shuttle run test and virtual system in healthy children: a cross-sectional study.BMC pediatrics · 2019Article
- Active Video Games for Rehabilitation in Respiratory Conditions: Systematic Review and Meta-Analysis.JMIR serious games · 2019Article
- Video Games for Well-Being: A Systematic Review on the Application of Computer Games for Cognitive and Emotional Training in the Adult Population.Frontiers in psychology · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim of the present study was to determine whether aerobic exercise involving an active video game system improved asthma control, airway inflammation and exercise capacity in children with moderate to severe asthma.
designA randomized, controlled, single-blinded clinical trial was carried out. Thirty-six children with moderate to severe asthma were randomly allocated to either a video game group (VGG; N = 20) or a treadmill group (TG; n = 16). Both groups completed an eight-week supervised program with two weekly 40-minute sessions. Pre-training and post-training evaluations involved the Asthma Control Questionnaire, exhaled nitric oxide levels (FeNO), maximum exercise testing (Bruce protocol) and lung function.
resultsNo differences between the VGG and TG were found at the baseline. Improvements occurred in both groups with regard to asthma control and exercise capacity. Moreover, a significant reduction in FeNO was found in the VGG (p < 0.05). Although the mean energy expenditure at rest and during exercise training was similar for both groups, the maximum energy expenditure was higher in the VGG.
conclusionThe present findings strongly suggest that aerobic training promoted by an active video game had a positive impact on children with asthma in terms of clinical control, improvement in their exercise capacity and a reduction in pulmonary inflammation.
trial registrationClinicaltrials.gov NCT01438294.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.