Evidence map›Paper›PMID 26301703›Full record

ArticleAIDS patient care and STDs2015

Fertility Decision-Making Among Kenyan HIV-Serodiscordant Couples Who Recently Conceived: Implications for Safer Conception Planning.

Jillian Pintye, Kenneth Ngure, Kathryn Curran, Sophie Vusha, Nelly Mugo, Connie Celum, Jared M Baeten, Renee Heffron

Open access · greenAbstract read
In one paragraph

Article in AIDS patient care and STDs, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 2 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. "Sexual and reproductive health matters · 2024
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  11. Living with Discordance: A Qualitative Description of the Challenges Faced by HIV Negative Married Women.International journal of community based nursing and midwifery · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Jillian Pintye1 Department of Global Health, University of Washington , Seattle, Washington.
Kenneth Ngure1 Department of Global Health, University of Washington , Seattle, Washington.
Kathryn Curran1 Department of Global Health, University of Washington , Seattle, Washington.
Sophie Vusha6 Center for Clinical Research, Kenya Medical Research Institute , Nairobi, Kenya .
Nelly Mugo1 Department of Global Health, University of Washington , Seattle, Washington.
Connie Celum1 Department of Global Health, University of Washington , Seattle, Washington.
Jared M Baeten1 Department of Global Health, University of Washington , Seattle, Washington.
Renee Heffron1 Department of Global Health, University of Washington , Seattle, Washington.
University of Washington · USJomo Kenyatta University of Agriculture and Technology · KEKenya Medical Research Institute · KE

Funding

Optimizing Antiretroviral-Based HIV Prevention for HIV Serodiscordant CouplesR01MH095507 · NIMH · UNIVERSITY OF WASHINGTON · PI BAETEN, JARED · 2011 to 2020
$6.1M
Antiretroviral periconception HIV prevention for HIV discordant couplesR00HD076679 · NICHD · UNIVERSITY OF WASHINGTON · PI HEFFRON, RENEE A. · 2015 to 2017
$742k
Evaluation of antiretroviral HIV prevention in African HIV discordant couplesR21NR012663 · NINR · UNIVERSITY OF WASHINGTON · PI BAETEN, JARED · 2011 to 2012
$376k
Antiretroviral periconception HIV prevention for HIV discordant couplesK99HD076679 · NICHD · UNIVERSITY OF WASHINGTON · PI HEFFRON, RENEE A. · 2013 to 2014
$208k
NICHD NIH HHS K99HD076679NICHD NIH HHS R00 HD076679NIMH NIH HHS R01 MH095507NINR NIH HHS R21NR012663
6 · The paper itself

Abstract

HIV-serodiscordant couples often choose to attempt pregnancy despite their HIV transmission risk. Optimizing delivery of HIV risk reduction strategies during peri-conception periods (i.e., safer conception) requires understanding how HIV-serodiscordant couples approach fertility decisions. We conducted 36 in-depth individual interviews with male and female partners of Kenyan heterosexual HIV-serodiscordant couples who recently conceived. Transcripts were analyzed by gender and HIV serostatus using open coding. Matrices were used to identify patterns and emerging themes. Most participants expressed acceptance of being in an HIV-serodiscordant couple and affirmed their resilience to live with serodiscordance and achieve their fertility goals. Overall, while the goal for childbearing was unchanged, conception became an urgent desire so that both partners could experience childrearing together while the HIV-infected partner was still healthy. Children also add value to the relationship, and multiple children were a commonly expressed desire. Couples' desires dominated those of individual partners in fertility decision-making, but male preferences were more influential when the individual desires differed. Values and preferences of the couple as a unit may mediate fertility decision-making in HIV-discordant couples. Thus, it is important that safer conception programs include both partners when appropriate and consider the relationship context during risk reduction counseling and when recommending risk reduction interventions.

Indexed as

Decision MakingFamily CharacteristicsFertilityAdultBlack PeopleCounselingFemaleHIV InfectionsHIV SeronegativityHumansInfectious Disease Transmission, VerticalInterviews as TopicMalePregnancyPregnancy Complications, InfectiousQualitative Research

Identifiers

PMID26301703
PMCPMC4553369
OpenAlexW2132233474

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.