Evidence map›Paper›PMID 26301177›Full record

ArticleInjury epidemiology2015

Effects of minimum legal drinking age on alcohol and marijuana use: evidence from toxicological testing data for fatally injured drivers aged 16 to 25 years.

Katherine M Keyes, Joanne E Brady, Guohua Li

Open access · goldAbstract read
In one paragraph

Article in Injury epidemiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. Evidence Base on Outpatient Behavioral Treatments for Adolescent Substance Use, 2014-2017: Outcomes, Treatment Delivery, and Promising Horizons.Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53
    Pooled it
  2. Article
  3. Article
  4. Road traffic injuries and substance use among emergency department patients in the Dominican Republic and Peru.Revista panamericana de salud publica = Pan American journal of public health · 2021
    Article
  5. Diverging Trends in the Relationship Between Binge Drinking and Depressive Symptoms Among Adolescents in the U.S. From 1991 Through 2018.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Katherine M KeyesDepartment of Epidemiology, Columbia University, Mailman School of Public Health, 722 West 168th Street, Suite 503, New York, NY 10032, USA.
Joanne E BradyDepartment of Epidemiology, Columbia University, Mailman School of Public Health, 722 West 168th Street, Suite 503, New York, NY 10032, USA ; Department of Anesthesiology, Columbia University, New York, NY, USA.
Guohua LiDepartment of Epidemiology, Columbia University, Mailman School of Public Health, 722 West 168th Street, Suite 503, New York, NY 10032, USA ; Department of Anesthesiology, Columbia University, New York, NY, USA.
Columbia University · US

Funding

Columbia Injury Control Research CenterR49CE002096 · CE · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI LI, GUOHUA · 2012 to 2018
$5.5M
Race, alcohol consumption and vehicle crashes: an epidemiologic paradoxK01AA021511 · NIAAA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI KEYES, KATHERINE M. · 2013 to 2017
$904k
Effectiveness of Mandatory Prescription Drug MonitoringR21DA029670 · NIDA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI LI, GUOHUA · 2011 to 2012
$418k
ACL HHS R49CE002096NCIPC CDC HHS R49 CE002096NIAAA NIH HHS K01 AA021511NIDA NIH HHS R21 DA029670
6 · The paper itself

Abstract

backgroundAlcohol and marijuana are among the most commonly used drugs by adolescents and young adults. The question of whether these two drugs are substitutes or complements has important implications for public policy and prevention strategies, especially as laws regarding the use of marijuana are rapidly changing.

methodsData were drawn from fatally injured drivers aged 16 to 25 who died within 1 h of the crash in nine states with high rates of toxicology testing based from 1999 to 2011 on the Fatality Analysis Reporting System (N = 7,191). Drug tests were performed using chromatography and radioimmunoassay techniques based on blood and/or urine specimens. Relative risk regression and Joinpoint permutation analysis were used.

resultsOverall, 50.5% of the drivers studied tested positive for alcohol or marijuana. Univariable relative risk modeling revealed that reaching the minimum legal drinking age was associated with a 14% increased risk of alcohol use (RR = 1.14, 95% CI: 1.02 to 1.28), a 24% decreased risk of marijuana use (RR = 0.76, 95% CI: 0.53 to 1.10), and a 22% increased risk of alcohol plus marijuana use (RR=1.22, 95% CI: 0.90 to 1.66). Joinpoint permutation analysis indicated that the prevalence of alcohol use by age is best described by two slopes, with a change at age 21. There was limited evidence for a change at age 21 for marijuana use.

conclusionsThese results suggest that among adolescents and young adults, increases in alcohol availability after reaching the MLDA have marginal effect on marijuana use.

Indexed as

AlcoholComplementsFARSMarijuanaMinimum legal drinking ageSubstitution

Identifiers

PMID26301177
PMCPMC4539964
OpenAlexW2121984528

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.