ArticleCurrent addiction reports2015
Psychological and Neurobiological Precursors of Alcohol Use Disorders in High Risk Youth.
Article in Current addiction reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 20 citations in OpenAlex.
- Dimensions of Craving Interact withBrain sciences · 2021Article
- GRM8 genotype is associated with externalizing disorders and greater inter-trial variability in brain activation during a response inhibition task.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2020Article
- Density and Dichotomous Family History Measures of Alcohol Use Disorder as Predictors of Behavioral and Neural Phenotypes: A Comparative Study Across Gender and Race/Ethnicity.Alcoholism, clinical and experimental research · 2020Article
- Attentional bias and response inhibition in severe obesity with food disinhibition: a study of P300 and N200 event-related potential.International journal of obesity (2005) · 2020Article
- Attentional and Neural Processing of Affective and Alcohol-Related Images in University-Attending Emerging Adults.Emerging adulthood (Print) · 2018Article
- Cortical thickness and trait empathy in patients and people at high risk for alcohol use disorders.Psychopharmacology · 2017Article
- Neural predictors of substance use disorders in Young adulthood.Psychiatry research. Neuroimaging · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
It has long been known that Alcohol Use Disorders (AUDs) run in families with substantial heritability. Determining the specific genetic underpinnings of these disorders has been challenging because of the clinical heterogeneity and variable expression across the lifespan. The search for endophenotypic biological variation associated with the AUD and related substance use disorder (SUD) phenotypes is based on the belief that an endophenotype is more proximal to the causative gene. Identification of genes conferring increased susceptibility has important implications for treatment through the potential development of medications that target specific genetic pathways. High risk family designs that contrast offspring with and without a familial/genetic background have provided valuable insights into the psychological characteristics (executive control, affective regulation, decision making and social cognition) that differentiate such individuals. The current chapter will review these with a focus on brain morphology of specific regions, the coordinated activity of neural networks, and developmental trajectories of electrophysiological activity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.