ArticleFrontiers in microbiology2015
Sulfonamide and tetracycline resistance genes in total- and culturable-bacterial assemblages in South African aquatic environments.
Article in Frontiers in microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.
- Contributions and Challenges of High Throughput qPCR for Determining Antimicrobial Resistance in the Environment: A Critical Review.Molecules (Basel, Switzerland) · 2019Pooled it
- Antibiotic resistance inFrontiers in microbiology · 2026Article
- Interactive networks of donors and recipients of the TetM gene and its evolutionary dynamics across the bacterial domain.Scientific reports · 2025Article
- First national study on genomic profiling ofEnvironmental challenges (Amsterdam, Netherlands) · 2025Article
- Bacterial community composition, quantification of antibiotic resistance genes and antibiotic residues in wastewater treatment plant and receiving rivers.Frontiers in microbiology · 2025Article
- Antibiotic Concentrations in Aquatic Environments of the African Continent: A Systematic Review and Predicted No-Effect Concentration (PNEC) Assessment.Environmental health insights · 2025Review
- Occurrence of Trace-Level Antibiotics in the Msunduzi River: An Investigation into South African Environmental Pollution.Antibiotics (Basel, Switzerland) · 2024Article
- Antibiotic-resistant bacteria in bovine milk in India.Journal of advanced veterinary and animal research · 2023Article
- Digestate from Agricultural Biogas Plants as a Reservoir of Antimicrobials and Antibiotic Resistance Genes-Implications for the Environment.International journal of environmental research and public health · 2023Article
- Antimicrobial Susceptibility Profiles amongPathogens (Basel, Switzerland) · 2022Article
- Environmental and Anthropogenic Factors Shape the Snow Microbiome and Antibiotic Resistome.Frontiers in microbiology · 2022Article
- The role of artificial intelligence in the battle against antimicrobial-resistant bacteria.Current genetics · 2021Review
- The Contribution of Wastewater to the Transmission of Antimicrobial Resistance in the Environment: Implications of Mass Gathering Settings.Tropical medicine and infectious disease · 2020Review
- Systematic review in South Africa reveals antibiotic resistance genes shared between clinical and environmental settings.Infection and drug resistance · 2018Review
- Release of Antibiotic Resistant Bacteria by a Waste Treatment Plant from Romania.Microbes and environments · 2017Article
- Article
- Hospital Effluents Are One of Several Sources of Metal, Antibiotic Resistance Genes, and Bacterial Markers Disseminated in Sub-Saharan Urban Rivers.Frontiers in microbiology · 2016Article
- Use of Aeromonas spp. as General Indicators of Antimicrobial Susceptibility among Bacteria in Aquatic Environments in Thailand.Frontiers in microbiology · 2016Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Antibiotic resistant bacteria are ubiquitous in the natural environment. The introduction of effluent derived antibiotic resistance genes (ARGs) into aquatic environments is of concern in the spreading of genetic risk. This study showed the prevalence of sulfonamide and tetracycline resistance genes, sul1, sul2, sul3, and tet(M), in the total bacterial assemblage and colony forming bacterial assemblage in river and estuarine water and sewage treatment plants (STP) in South Africa. There was no correlation between antibiotic concentrations and ARGs, suggesting the targeted ARGs are spread in a wide area without connection to selection pressure. Among sul genes, sul1 and sul2 were major genes in the total (over 10(-2) copies/16S) and colony forming bacteria assemblages (∼10(-1) copies/16S). In urban waters, the sul3 gene was mostly not detectable in total and culturable assemblages, suggesting sul3 is not abundant. tet(M) was found in natural assemblages with 10(-3) copies/16S level in STP, but was not detected in colony forming bacteria, suggesting the non-culturable (yet-to-be cultured) bacterial community in urban surface waters and STP effluent possess the tet(M) gene. Sulfamethoxazole (SMX) resistant (SMX(r)) and oxytetracycline (OTC) resistant (OTC(r)) bacterial communities in urban waters possessed not only sul1 and sul2 but also sul3 and tet(M) genes. These genes are widely distributed in SMX(r) and OTC(r) bacteria. In conclusion, urban river and estuarine water and STP effluent in the Durban area were highly contaminated with ARGs, and the yet-to-be cultured bacterial community may act as a non-visible ARG reservoir in certain situations.
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