ArticleCurrent oncology (Toronto, Ont.)2015
Fertility preservation in reproductive-age women facing gonadotoxic treatments.
Article in Current oncology (Toronto, Ont.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- The impact of BRCA mutation and hormone receptor status on the outcomes of fertility preservation in breast cancer patients: a systematic review and meta-analysis.Frontiers in oncology · 2025Pooled it
- Gonadotropin-Releasing Hormone Analogs for Gonadal Protection During Gonadotoxic Chemotherapy: A Systematic Review and Meta-Analysis.Reproductive sciences (Thousand Oaks, Calif.) · 2019Pooled it
- Research progress on multi-mechanism analysis and protection strategies of ovarian aging and fertility decline.Journal of ovarian research · 2026Review
- Predictors of fertility preservation awareness and willingness among college students and the general population in Henan, China: a cross-sectional study.Frontiers in public health · 2026Article
- Fertility in early breast cancer patients: integrating reproductive planning into oncology care.Frontiers in endocrinology · 2025Review
- Vitrification alters growth differentiation factor 9 and follicle-stimulating hormone receptor expression in human cumulus-mural granulosa cells.Clinical and experimental reproductive medicine · 2024Article
- Investigating Ovulation Induction Outcomes in Patients with Decreased Ovarian Reserve Treated with Double Stimulation during The Follicular and Luteal Phases Compared to The Conventional Antagonist Cycle: A Randomized Clinical Trial.International journal of fertility & sterility · 2024Article
- The Usage of Cryopreserved Reproductive Material in Cancer Patients Undergoing Fertility Preservation Procedures.Cancers · 2023Review
- Protective Effect ofAnimals : an open access journal from MDPI · 2022Article
- Fertility after Cancer: Risks and Successes.Cancers · 2022Review
- Barriers to Oncofertility Care among Female Adolescent Cancer Patients in Canada.Current oncology (Toronto, Ont.) · 2022Review
- Fertility preservation is an imperative goal in the clinical practice of radiation oncology: a narrative review.Ecancermedicalscience · 2022Review
- Contemporary Fertility-Sparing Management Options of Early Stage Endometrioid Endometrial Cancer in Young Nulliparous Patients.Journal of clinical medicine · 2021Review
- Reproductive concerns and fear of cancer recurrence: a qualitative study of women's experiences of the perinatal period after cancer.BMC pregnancy and childbirth · 2021Article
- Laparoscopic Ovarian Transposition and Ovariopexy for Fertility Preservation in Patients Treated with Pelvic Radiotherapy with or without Chemotherapy.Facts, views & vision in ObGyn · 2019Article
- How can we improve oncofertility care for patients? A systematic scoping review of current international practice and models of care.Human reproduction update · 2019Article
- Fertility preservation for female cancer patients.International journal of clinical oncology · 2019Review
- Fertility preservation in post-pubescent female cancer patients: A practical guideline for clinicians.Molecular and clinical oncology · 2018Article
- Listening through narratives: using a narrative approach when discussing fertility preservation options with young cancer patients.Current oncology (Toronto, Ont.) · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAdvancements in the treatments for cancer and autoimmune and other hematologic conditions continue to improve survival and cure rates. Despite those changes, various gonadotoxic agents and other treatments can still compromise the future fertility of many women. Progress in medical and surgical reproductive technologies has helped to offset the reproductive consequences of the use of gonadotoxic therapies, and allows for future fertility and normal pregnancy.
methodsA review of the literature was performed to outline the pathophysiology of gonadotoxicity from various treatments. The success of fertility preservation, fertility sparing, and cryopreservation options are reviewed. Barriers and facilitators to referral and oncofertility treatment in Canada are also outlined.
resultsAccording to the quality of the evidence, recommendations are made for fertility assessment, patient referral, cryopreservation, and other assisted reproductive technologies.
conclusionsTo ensure ongoing fertility in women undergoing gonadotoxic treatments, assisted reproductive technologies can be combined with a multidisciplinary approach to patient assessment and referral.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.