Evidence map›Paper›PMID 26300319›Full record

ArticleFungal genetics and biology : FG & B2015

Genome analysis and polar tube firing dynamics of mosquito-infecting microsporidia.

Emily R Troemel, James J Becnel

Abstract read
In one paragraph

Article in Fungal genetics and biology : FG & B, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Cryo-ET reveals the in situ architecture of the polar tube invasion apparatus from microsporidian parasites.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Article
  4. Article
  5. Review
  6. Germination of Microsporidian Spores: The Known and Unknown.Journal of fungi (Basel, Switzerland) · 2023
    Review
  7. Mechanics of Microsporidian Polar Tube Firing.Experientia supplementum (2012) · 2022
    Article
  8. Comparative Genomics of Microsporidia.Experientia supplementum (2012) · 2022
    Article
  9. Article
  10. Article
  11. Quantitative Proteomic Analysis of Germination ofFrontiers in microbiology · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Emily R TroemelDivision of Biological Sciences, Section of Cell and Developmental Biology, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, United States. Electronic address: etroemel@ucsd.edu.
James J BecnelUSDA, ARS, CMAVE, 1600 S.W. 23rd Drive, Gainesville, FL 32608, United States. Electronic address: James.Becnel@ars.usda.gov.
Agricultural Research Service · USUniversity of California, San Diego · US

Funding

The Intracellular Pathogen Response Triggers Defense Against Co-evolved PathogensR01GM114139 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Emily R Troemel · 2015 to 2026
$3.1M
A natural host model for microsporidia pathogenesis in the intestineR01AI087528 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI TROEMEL, EMILY R · 2010 to 2014
$1.9M
NIAID NIH HHS R01 AI087528NIGMS NIH HHS R01 GM114139
6 · The paper itself

Abstract

Microsporidia are highly divergent fungi that are obligate intracellular pathogens of a wide range of host organisms. Here we review recent findings from the genome sequences of mosquito-infecting microsporidian species Edhazardia aedis and Vavraia culicis, which show large differences in genome size, although similar numbers of predicted genes. We also show a video of E. aedis polar tube firing, which is the dramatic mechanism used by microsporidia to deliver the germ cell (sporoplasm) into the host cell to initiate intracellular infection.

Indexed as

Genome, FungalAnimalsCulicidaeGenome SizeGerm CellsHost-Pathogen InteractionsMicrosporidiaAedes aegyptiEdhazardia aedisGenome sequenceMicrosporidiaMosquitoPolar tubeVavraia culicis

Identifiers

PMID26300319
PMCPMC4587305
OpenAlexW1672518371

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.