Evidence map›Paper›PMID 26299772›Full record

ArticleMedical science monitor : international medical journal of experimental and clinical research2015

Semen Quality, Hormonal Levels, and Androgen Receptor Gene Polymorphisms in a Population of Young Male Volunteers from Two Different Regions of Poland.

Marzena Kamieniczna, Monika Fraczek, Agnieszka Malcher, Natalia Rozwadowska, Anna Czernikiewicz, Piotr Jedrzejczak, Marian Semczuk, Maciej Kurpisz

Open access · hybridAbstract read
In one paragraph

Article in Medical science monitor : international medical journal of experimental and clinical research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Spatiotemporal trends in human semen quality.Nature reviews. Urology · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Marzena KamienicznaDepartment of Reproductive Biology and Stem Cells, Institute of Human Genetics, Polish Academy of Sciences, Poznań, Poland.
Monika FraczekDepartment of Reproductive Biology and Stem Cells, Institute of Human Genetics Polish Academy of Sciences, Poznań, Poland.
Agnieszka MalcherDepartment of Reproductive Biology and Stem Cells, Institute of Human Genetics Polish Academy of Sciences, Poznań, Poland.
Natalia RozwadowskaDepartment of Reproductive Biology and Stem Cells, Institute of Human Genetics Polish Academy of Sciences, Poznań, Poland.
Anna CzernikiewiczDepartment of Reproductive Biology and Stem Cells, Institute of Human Genetics Polish Academy of Sciences, Poznań, Poland.
Piotr JedrzejczakDepartment of Gynecology, Obstetrics and Gynecological Oncology, Poznań University of Medical Sciences, Poznań, Poland.
Marian SemczukDepartment of Obstetrics and Pathology of Pregnancy, Medical University of Lublin, Lublin, Poland.
Maciej KurpiszDepartment of Reproductive Biology and Stem Cells, Institute of Human Genetics Polish Academy of Sciences, Poznań, Poland.
Institute of Human Genetics · PLMedical University of Lublin · PLPolish Academy of Sciences · PLPoznan University of Medical Sciences · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe population of healthy Polish men has not been frequently and systematically investigated for fertility status. The aim of this study was to assess the quality of semen in a randomly recruited population of young males. The most important task was to find a relationship between semen parameters, sex hormones, and AR gene polymorphism. MATERIAL AND

methodsSemen and blood samples from young men from the Poznan (n=113) and Lublin regions (n=89) were collected for semen analysis, assessment of hormonal concentrations, and calculation of the CAG and GGN repeats of the AR gene.

resultsStatistical comparisons of the hormones and circulating proteins and the seminological parameters revealed significant differences between the regional groups of males studied. Among the correlations found, we emphasize the positive relationship between inhibin B levels and both the number of spermatozoa per ml (R=0.37; p=0.0001) and the total sperm concentration (R=0.40; p=0.00003). Positive correlations between IGF1 and sperm morphology was also found (R=0.40; p=0.000004). The mean number of CAG repeats in our tested groups was 21.93±2.79, in a range from 16 to 31. The mean number of GGN repeats was 23.2±1.66 and ranged from 16 to 29. Numerous significant correlations were found between CAG or GGN repeats and blood hormones or circulating proteins and semen parameters; however, Spearman's rank correlations revealed rather weak coefficients.

conclusionsThis report attempted to determine the quality of semen samples and sex hormones in a population of Polish young men. The results were found to be similar to data obtained in Scandinavia. The calculated means and range of CAG or GGN repeats of the AR gene in Polish males were similar to West European epidemiological data.

Indexed as

Polymorphism, GeneticSemen AnalysisAdolescentAdultBlood ProteinsCohort StudiesGonadal Steroid HormonesHumansInhibinsMalePolandReceptors, AndrogenSperm CountSperm MotilityTrinucleotide RepeatsYoung AdultAR protein, humanBlood ProteinsGonadal Steroid Hormonesinhibin BInhibinsReceptors, Androgen

Identifiers

PMID26299772
PMCPMC4552290
OpenAlexW1864457931

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.