Evidence map›Paper›PMID 26299474›Full record

ArticleNeuron2015

Wide Dispersion and Diversity of Clonally Related Inhibitory Interneurons.

Corey C Harwell, Luis C Fuentealba, Adrian Gonzalez-Cerrillo, Phillip R L Parker, Caitlyn C Gertz, Emanuele Mazzola, Miguel Turrero Garcia, Arturo Alvarez-Buylla, Constance L Cepko, Arnold R Kriegstein

Open access · bronzeAbstract read
In one paragraph

Article in Neuron, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 102 citations in OpenAlex.

  1. Multimodal classification of neurons in the lateral septum.bioRxiv : the preprint server for biology · 2026
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  15. Morphology and Dendrite-Specific Synaptic Properties of Midbrain Neurons Shape Multimodal Integration.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022
    Article
  16. Article
  17. Review
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  19. From Progenitors to Progeny: Shaping Striatal Circuit Development and Function.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Review
  20. Article

4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Corey C HarwellDepartment of Neurobiology, Harvard Medical School, Boston, MA 02115, USA. Electronic address: corey_harwell@hms.harvard.edu.
Luis C FuentealbaDepartment of Neurological Surgery, University of California, San Francisco, San Francisco, CA 94143, USA; Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, San Francisco, CA 94143, USA.
Adrian Gonzalez-CerrilloDepartment of Neurobiology, Harvard Medical School, Boston, MA 02115, USA.
Phillip R L ParkerGladstone Institute for Neurological Disease, San Francisco, CA 94158, USA.
Caitlyn C GertzDepartment of Neurology, University of California, San Francisco, San Francisco, CA 94143, USA; Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, San Francisco, CA 94143, USA.
Emanuele MazzolaDepartment of Biostatistics, Harvard School of Public Health, Boston, MA 02115, USA.
Miguel Turrero GarciaDepartment of Neurobiology, Harvard Medical School, Boston, MA 02115, USA.
Arturo Alvarez-BuyllaDepartment of Neurological Surgery, University of California, San Francisco, San Francisco, CA 94143, USA; Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, San Francisco, CA 94143, USA.
Constance L CepkoDepartments of Genetics and Ophthalmology and Howard Hughes Medical Institute, Harvard Medical School, Boston, MA 02115, USA.
Arnold R KriegsteinDepartment of Neurology, University of California, San Francisco, San Francisco, CA 94143, USA; Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, San Francisco, CA 94143, USA.
Harvard University · USBroad Center · USGladstone Institutes · USNeurological Surgery · USUniversity of California, San Francisco · US

Funding

Heterogeneity of Adult Neural Stem CellsR37HD032116 · NICHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ALVAREZ-BUYLLA, ARTURO · 2008 to 2017
$4.7M
The Physiology of Radial Units in CorticogenesisR01NS035710 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KRIEGSTEIN, ARNOLD · 1997 to 2010
$3.3M
POSTNATAL NEURONAL PRECURSORS AND BRAIN REPAIRR01HD032116 · NICHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ALVAREZ-BUYLLA, ARTURO · 1994 to 2007
$1.7M
Howard Hughes Medical InstituteNICHD NIH HHS R01 HD032116NICHD NIH HHS R37 HD032116NICHD NIH HHS R37HD032116NINDS NIH HHS R01 NS035710NINDS NIH HHS R01NS035710
6 · The paper itself

Abstract

The mammalian neocortex is composed of two major neuronal cell types with distinct origins: excitatory pyramidal neurons and inhibitory interneurons, generated in dorsal and ventral progenitor zones of the embryonic telencephalon, respectively. Thus, inhibitory neurons migrate relatively long distances to reach their destination in the developing forebrain. The role of lineage in the organization and circuitry of interneurons is still not well understood. Utilizing a combination of genetics, retroviral fate mapping, and lineage-specific retroviral barcode labeling, we find that clonally related interneurons can be widely dispersed while unrelated interneurons can be closely clustered. These data suggest that migratory mechanisms related to the clustering of interneurons occur largely independent of their clonal origin.

Indexed as

Neural InhibitionAnimalsCell LineageCell MovementCells, CulturedCerebral CortexEmbryo, MammalianGreen Fluorescent ProteinsInterneuronsIn Vitro TechniquesLaser Capture MicrodissectionMiceNerve NetNerve Tissue ProteinsNeural Stem CellsOrgan Culture TechniquesGreen Fluorescent ProteinsNerve Tissue Proteins

Identifiers

PMID26299474
PMCPMC4581718
OpenAlexW2114586459

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.