ReviewCurrent neurology and neuroscience reports2015
Update on Hippocampal Sclerosis.
Review in Current neurology and neuroscience reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 36 citations in OpenAlex.
- Integrative single-cell and spatial transcriptomics combined with machine learning to discover complement-associated biomarkers in temporal lobe epilepsy with hippocampal sclerosis.Functional & integrative genomics · 2026Article
- Differences and potential mechanisms of theta oscillation and temporoparietal and temporal-central networks in temporal lobe epilepsy patients with unilateral hippocampal sclerosis.Acta epileptologica · 2024Article
- Deep brain stimulation of the subiculum in the treatment for refractory temporal lobe epilepsy due to unilateral mesial temporal lobe sclerosis.Epilepsy & behavior reports · 2024Article
- Severe CTE and TDP-43 pathology in a former professional soccer player with dementia: a clinicopathological case report and review of the literature.Acta neuropathologica communications · 2023Review
- Amygdala subnuclear volumes in temporal lobe epilepsy with hippocampal sclerosis and in non-lesional patients.Brain communications · 2022Article
- Hippocampal Malrotation Could Be Less Significant in Epilepsy Caused by Focal Cortical Dysplasia Type I and Type II.Frontiers in neurology · 2022Article
- Effects of seizure burden on structural global brain networks in patients with unilateral hippocampal sclerosis.Brain and behavior · 2021Article
- Alzheimer's Disease Neuropathological Comorbidities are Common in the Younger-Old.Journal of Alzheimer's disease : JAD · 2021Article
- Reduction of Retinal Thickness Ipsilateral to Hippocampal Sclerosis in Epilepsy.Frontiers in neurology · 2021Article
- HHV-6 and hippocampal volume in patients with mesial temporal sclerosis.Annals of clinical and translational neurology · 2020Article
- Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report.Brain : a journal of neurology · 2019Article
- TDP-43 and Limbic-Predominant Age-Related TDP-43 Encephalopathy.Frontiers in aging neuroscience · 2019Article
- Overlapping but distinct TDP-43 and tau pathologic patterns in aged hippocampi.Brain pathology (Zurich, Switzerland) · 2018Article
- Hippocampal Sclerosis in the Oldest Old: A Finnish Population-Based Study.Journal of Alzheimer's disease : JAD · 2018Article
- The Association Between Neurocysticercosis and Hippocampal Atrophy is Related to Age.The American journal of tropical medicine and hygiene · 2017Article
- Genomics and CSF analyses implicate thyroid hormone in hippocampal sclerosis of aging.Acta neuropathologica · 2016Article
- Case Studies Illustrating Focal Alzheimer's, Fluent Aphasia, Late-Onset Memory Loss, and Rapid Dementia.Neurologic clinics · 2016Review
- "New Old Pathologies": AD, PART, and Cerebral Age-Related TDP-43 With Sclerosis (CARTS).Journal of neuropathology and experimental neurology · 2016Review
- Hippocampal Sclerosis of Aging, a Common Alzheimer's Disease 'Mimic': Risk Genotypes are Associated with Brain Atrophy Outside the Temporal Lobe.Journal of Alzheimer's disease : JAD · 2016Article
- Untangling tau imaging.Alzheimer's & dementia (Amsterdam, Netherlands) · 2016Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The diagnostic hallmarks of hippocampal sclerosis (HS) are severe volume loss of the hippocampus, severe neuronal loss, and reactive gliosis involving primarily two especially vulnerable fields, CA1 and the subiculum. Occasionally, HS may be the only neuropathological change detected in older individuals with dementia and is known as pure HS. In the majority of cases, HS occurs in the setting of other degenerative changes, usually Alzheimer's disease (AD). In these cases, it is classified as combined HS. Although a clinical profile for HS has been identified, its similarities with AD make the diagnosis during life quite challenging; thus, the diagnosis is often made postmortem. The pathogenesis of HS is not completely understood, but the strong association with transactive response DNA-binding protein 43 (TDP-43), in approximately 90%, and the recent discovery of genetic risk factors are important contributions to a better understanding of the disease process.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.