Evidence map›Paper›PMID 26298770›Full record

ReviewTrends in neurosciences2015

New neurons in the adult striatum: from rodents to humans.

Dragos Inta, Heather A Cameron, Peter Gass

Open access · greenAbstract readReview
In one paragraph

Review in Trends in neurosciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 62 citations in OpenAlex.

  1. Review
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  14. An Overview of Adult Neurogenesis.Advances in experimental medicine and biology · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Dragos IntaDepartment of Psychiatry and Psychotherapy, RG Animal Models in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim/Heidelberg University, Heidelberg, Germany. Electronic address: Dragos.Inta@zi-mannheim.de.
Heather A CameronSection on Neuroplasticity, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA.
Peter GassDepartment of Psychiatry and Psychotherapy, RG Animal Models in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim/Heidelberg University, Heidelberg, Germany.
Central Institute of Mental Health · DEHeidelberg University · DENational Institutes of Health · US

Funding

Neurogenesis In The Adult BrainZIAMH002784 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI CAMERON, HEATHER A · 2009 to 2025
$29.7M
Intramural NIH HHS ZIA MH002784PHS HHS 1ZIAMH002784
6 · The paper itself

Abstract

Most neurons are generated during development and are not replaced during adulthood, even if they are lost to injury or disease. However, it is firmly established that new neurons are generated in the dentate gyrus of the hippocampus of almost all adult mammals, including humans. Nevertheless, many questions remain regarding adult neurogenesis in other brain regions and particularly in humans, where standard birth-dating methods are not generally feasible. Exciting recent evidence indicates that calretinin-expressing interneurons are added to the adult human striatum at a substantial rate. The role of new neurons is unknown, but studies in rodents will be able to further elucidate their identity and origin and then we may begin to understand their regulation and function.

Indexed as

AgingAnimalsCorpus StriatumHumansNeurogenesisNeuronsadult neurogenesisGABAergic interneuronshumansstriatumsubventricular zone

Identifiers

PMID26298770
PMCPMC4564523
OpenAlexW1558857410

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.