Evidence map›Paper›PMID 26298443›Full record

SynthesisInternational journal of public health2015

Considering treatment of male genital schistosomiasis as a tool for future HIV prevention: a systematic review.

Chalotte Willemann Stecher, Per Kallestrup, Eyrun Floerecke Kjetland, Birgitte Vennervald, Eskild Petersen

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in International journal of public health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
3.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.

  1. Association of schistosomiasis and HIV infections: A systematic review and meta-analysis.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2021
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  17. Impact of Endemic Infections on HIV Susceptibility in Sub-Saharan Africa.Tropical diseases, travel medicine and vaccines · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 3 countries.

Chalotte Willemann StecherDepartment of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark. chalstec@rm.dk.ORCID http://orcid.org/0000-0002-2774-3264
Per KallestrupCenter for Global Health (GloHAU), Aarhus University, Aarhus, Denmark. kallestrup@dadlnet.dk.
Eyrun Floerecke KjetlandNorwegian Centre for Imported and Tropical Diseases, Oslo University Hospital, Oslo, Norway. e.f.kjetland@medisin.uio.no.
Birgitte VennervaldDepartment of Parasitology and Aquatic Diseases, University of Copenhagen, Copenhagen, Denmark. bjv@sund.ku.dk.
Eskild PetersenDepartment of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark. joepeter@rm.dk.
Aarhus University · DKAarhus University Hospital · DKOslo University Hospital · NOUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesMale genital schistosomiasis (MGS) is a neglected manifestation of Schistosoma haematobium infection with ignored implications on reproductive health and a differential diagnosis to sexually transmitted infections in endemic regions. MGS may have associations with HIV transmission and acquisition, and treatment could be a neglected chance of HIV prevention. This review summarizes current knowledge on epidemiology, clinical manifestations, diagnosis and treatment of MGS as a hypothesized risk factor for HIV transmission. Future research areas of global interest are suggested.

methodsPubMed published literature was reviewed based on the MOOSE guidelines. All publications on MGS were included regardless of publication year and study design. Furthermore, all publications were searched for information on possible HIV association.

resultsThe 40 identified publications related to MGS were dominated by case reports and observational studies. No randomized clinical trials have been conducted to date, and very scant information related to possible associations with HIV transmission was presented.

conclusionsClinical, randomized studies and epidemiological studies covering the possible association between MGS and HIV are urgently needed. Furthermore, field diagnostic tools should be developed and future mass treatment programs should include adults to reduce morbidity and prevent HIV acquisition. SYSTEMATIC REVIEW REGISTRATION NUMBER: CRD42015016252.

Indexed as

HIV-1AdultAnimalsEndemic DiseasesHIV InfectionsHumansMalePraziquantelRisk FactorsSchistosoma haematobiumSchistosomiasis haematobiaSchistosomicidesSexually Transmitted DiseasesVirus SheddingPraziquantelSchistosomicidesGenitalHIVMaleMGSSchistosomiasis

Identifiers

PMID26298443
OpenAlexW1719206675

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.