Evidence map›Paper›PMID 26298333›Full record

ReviewSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2015

Clinical efficacy of denosumab versus bisphosphonates for the prevention of bone complications: implications for nursing.

Cynthia Campbell-Baird, Stacey Harrelson, Georgette Frey, Arun Balakumaran

Abstract readReview
PubMed Publisher
In one paragraph

Review in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. A cross-sectional study on Chinese oncology nurses' knowledge of bone health among cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Article
  2. Management of bone health in patients with cancer: a survey of specialist nurses.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Cynthia Campbell-BairdDepartment of Oncology, Penn State Hershey Medical Center, 500 University Drive, H046, C6615, Hershey, PA, 17033, USA. cbaird@hmc.psu.edu.
Stacey HarrelsonCarolina Urologic Research Center, 823 82nd Parkway, Suite B, Myrtle Beach, SC, 29572, USA.
Georgette FreyArizona Cancer Center, University of Arizona, 1515 North Campbell Avenue, Tucson, AZ, 85724, USA.
Arun BalakumaranAmgen Inc., One Amgen Center Drive, Thousand Oaks, CA, 91320, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antiresorptive therapies are used for the prevention of skeletal-related events (SREs) associated with metastatic bone disease related to breast cancer, prostate cancer, and other solid tumors. This review highlights the central role of nurses in supporting and educating advanced cancer patients regarding the consequences of bone metastases and SREs, including therapy management options. Contemporary clinical journals reporting evidence-based studies were reviewed. SREs associated with bone metastases can significantly impact the quality of life of advanced cancer patients. Denosumab therapy, an advancement in antiresorptive treatments, significantly prevents and delays the time to develop SREs. In the multifaceted approach required for successful and consistent management of SREs associated with bone metastases, antiresorptive therapies can play a central role in maintaining the functional independence of patients through the prevention of debilitating SREs, thereby preserving quality of life.

Indexed as

Antibodies, Monoclonal, HumanizedBone NeoplasmsDenosumabDiphosphonatesFemaleHumansMaleNursingQuality of LifeTreatment OutcomeAntibodies, Monoclonal, HumanizedDenosumabDiphosphonatesAntiresorptiveBisphosphonatesBone metastasesDenosumabSkeletal-related events

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.