Evidence map›Paper›PMID 26297373›Full record

ArticleBMJ open2015

Mortality from treatable illnesses in marginally housed adults: a prospective cohort study.

Andrea A Jones, Fidel Vila-Rodriguez, Olga Leonova, Verena Langheimer, Donna J Lang, Alasdair M Barr, Ric M Procyshyn, Geoffrey N Smith, Krista Schultz, Tari Buchanan and 7 more

Abstract read
In one paragraph

Article in BMJ open, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  16. The Cedar Project: mortality among young Indigenous people who use drugs in British Columbia.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Andrea A JonesDepartment of Psychiatry, University of British Columbia, Vancouver, British Columbia, Canada.
Fidel Vila-RodriguezDepartment of Psychiatry, University of British Columbia, Vancouver, British Columbia, Canada.
Olga LeonovaDepartment of Psychiatry, University of British Columbia, Vancouver, British Columbia, Canada.
Verena LangheimerDepartment of Psychiatry, University of British Columbia, Vancouver, British Columbia, Canada.
Donna J LangDepartment of Radiology, University of British Columbia, Vancouver, British Columbia, Canada.
Alasdair M BarrDepartment of Anesthesia, Pharmacology and Therapeutics, University of British Columbia, Vancouver, British Columbia, Canada.
Ric M ProcyshynDepartment of Psychiatry, University of British Columbia, Vancouver, British Columbia, Canada.
Geoffrey N SmithDepartment of Psychiatry, University of British Columbia, Vancouver, British Columbia, Canada.
Krista SchultzDepartment of Psychiatry, University of British Columbia, Vancouver, British Columbia, Canada.
Tari BuchananDepartment of Psychiatry, University of British Columbia, Vancouver, British Columbia, Canada.
Michael KrauszDepartment of Psychiatry, University of British Columbia, Vancouver, British Columbia, Canada.
Julio S MontanerDepartment of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
G William MacEwanDepartment of Psychiatry, University of British Columbia, Vancouver, British Columbia, Canada.
Alexander RauscherDepartment of Pediatrics, University of British Columbia, Vancouver, British Columbia, Canada.
William J PanenkaDepartment of Psychiatry, University of British Columbia, Vancouver, British Columbia, Canada.
Allen E ThorntonDepartment of Psychology, Simon Fraser University, Burnaby, British Columbia, Canada.
William G HonerDepartment of Psychiatry, University of British Columbia, Vancouver, British Columbia, Canada.

Funding

Canadian Institutes of Health Research 201109MSH-261306-183304Canadian Institutes of Health Research CBG-101827Canadian Institutes of Health Research MOP-137103
6 · The paper itself

Abstract

objectivesSocially disadvantaged people experience greater risk for illnesses that may contribute to premature death. This study aimed to evaluate the impact of treatable illnesses on mortality among adults living in precarious housing.

designA prospective cohort based in a community sample.

settingA socially disadvantaged neighbourhood in Vancouver, Canada.

participantsAdults (N=371) living in single room occupancy hotels or recruited from the Downtown Community Court and followed for median 3.8 years.

main outcome measuresParticipants were assessed for physical and mental illnesses for which treatment is currently available. We compared cohort mortality rates with 2009 Canadian rates. Left-truncated Cox proportional hazards modelling with age as the time scale was used to assess risk factors for earlier mortality.

resultsDuring 1269 person-years of observation, 31/371 (8%) of participants died. Compared with age-matched and sex-matched Canadians, the standardised mortality ratio was 8.29 (95% CI 5.83 to 11.79). Compared with those that had cleared the virus, active hepatitis C infection was a significant predictor for hepatic fibrosis adjusting for alcohol dependence and age (OR=2.96, CI 1.37 to 7.08). Among participants <55 years of age, psychosis (HR=8.12, CI 1.55 to 42.47) and hepatic fibrosis (HR=13.01, CI 3.56 to 47.57) were associated with earlier mortality. Treatment rates for these illnesses were low (psychosis: 32%, hepatitis C virus: 0%) compared with other common disorders (HIV: 57%, opioid dependence: 61%) in this population.

conclusionsHepatic fibrosis and psychosis are associated with increased mortality in people living in marginal conditions. Timely diagnosis and intervention could reduce the high mortality in marginalised inner city populations.

Indexed as

HousingMortalityAdultCanadaCause of DeathCommunicable DiseasesFemaleHepatitis CHumansIll-Housed PersonsLiver CirrhosisMaleMental DisordersMiddle AgedProspective StudiesRisk FactorsINFECTIOUS DISEASESPUBLIC HEALTH

Identifiers

PMID26297373
PMCPMC4550735

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.