ArticleEuropean journal of epidemiology2016
Associations between early body mass index trajectories and later metabolic risk factors in European children: the IDEFICS study.
Article in European journal of epidemiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- Skeletal Muscle Mass Measured Noninvasively by DJournal of pediatrics. Clinical practice · 2025Article
- Classification of childhood obesity using longitudinal clinical body mass index and its validation.International journal of obesity (2005) · 2025Observational
- Epidemiology of metabolic syndrome.Pflugers Archiv : European journal of physiology · 2025Review
- Long-term impact of maternal pre-pregnancy BMI on the risk of overweight/obesity in preschool children: mediation by infant birth weight and BMI trajectory group from 0 to 2 years.BMC public health · 2024Article
- The association of long-term trajectories of BMI, its variability, and metabolic syndrome: a 30-year prospective cohort study.EClinicalMedicine · 2024Article
- Postnatal growth in small vulnerable newborns: a longitudinal study of 2 million Brazilians using routine register-based linked data.The American journal of clinical nutrition · 2024Article
- The impact of body composition and fat distribution on blood pressure in young and middle-aged adults.Frontiers in nutrition · 2022Article
- Body Mass Index Changes and Insulin Resistance at Age 4: A Prospective Cohort Study.Frontiers in endocrinology · 2022Article
- Investigating Relationships between Preschool Children's Perceived Competence, Motor Skills, and Physical Activity: A Cross-Lagged Panel Model.Journal of clinical medicine · 2021Article
- Body mass index trajectory from childhood to puberty and high blood pressure: the China Health and Nutrition Survey.BMJ open · 2021Article
- Resolving early obesity leads to a cardiometabolic profile within normal ranges at 23 years old in a two-decade prospective follow-up study.Scientific reports · 2021Article
- Fat Mass Accretion from Birth to 5 Years and Metabolic Homeostasis in Childhood: the Healthy Start Study.The Journal of clinical endocrinology and metabolism · 2021Observational
- Associations between Prenatal Exposure to Phthalates and Timing of Menarche and Growth and Adiposity into Adulthood: A Twenty-Years Birth Cohort Study.International journal of environmental research and public health · 2021Article
- Targeting Parenting Quality to Reduce Early Life Adversity Impacts on Lifespan Cardiometabolic Risk.Frontiers in psychology · 2021Review
- Trajectories of early to mid-life adulthood BMI and incident diabetes: the China Health and Nutrition Survey.BMJ open diabetes research & care · 2020Article
- BMI Trajectories from Birth to 23 Years by Cardiometabolic Risks in Young Adulthood.Obesity (Silver Spring, Md.) · 2020Article
- Prevalence of severe/morbid obesity and other weight status and anthropometric reference standards in Spanish preschool children: The PREFIT project.Pediatric research · 2020Article
- Long-term vs. recent-onset obesity: their contribution to cardiometabolic risk in adolescence.Pediatric research · 2019Article
- Impact of the intervention program "JolinchenKids - fit and healthy in daycare" on energy balance related-behaviors: results of a cluster controlled trial.BMC pediatrics · 2019Article
- Association of accelerated body mass index gain with repeated measures of blood pressure in early childhood.International journal of obesity (2005) · 2019Article
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Authors and funding
12 authors.
Funding
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Abstract
Faster growth seems to be a common factor in several hypotheses relating early life exposures to subsequent health. This study aims to investigate the association between body mass index (BMI) trajectories during infancy/childhood and later metabolic risk in order to identify sensitive periods of growth affecting health. In a first step, BMI trajectories of 3301 European children that participated in the multi-centre Identification and Prevention of Dietary and Lifestyle-induced Health Effects in Children and Infants (IDEFICS) study were modelled using linear-spline mixed-effects models. The estimated random coefficients indicating initial subject-specific BMI and rates of change in BMI over time were used as exposure variables in a second step and related to a metabolic syndrome (MetS) score and its single components based on conditional regression models (mean age at outcome assessment: 8.5 years). All exposures under investigation, i.e. BMI at birth, rates of BMI change during infancy (0 to <9 months), early childhood (9 months to <6 years) and later childhood (≥6 years) as well as current BMI z-score were significantly associated with the later MetS score. Associations were strongest for the rate of BMI change in early childhood (1.78 [1.66; 1.90]; β estimate and 99 % confidence interval) and current BMI z-score (1.16 [0.96; 1.38]) and less pronounced for BMI at birth (0.62 [0.47; 0.78]). Results slightly differed with regard to the single metabolic factors. Starting from birth rapid BMI growth, especially in the time window of 9 months to <6 years, is significantly related to later metabolic risk in children. Much of the associations of early BMI growth may further be mediated through the effects on subsequent BMI growth.
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