Evidence map›Paper›PMID 26297173›Full record

SynthesisJournal of evidence-based complementary & alternative medicine2016

A Systematic Review of Iran's Medicinal Plants With Anticancer Effects.

Majid Asadi-Samani, Wesam Kooti, Elahe Aslani, Hedayatollah Shirzad

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Journal of evidence-based complementary & alternative medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
9.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 106 citations in OpenAlex.

  1. Article
  2. Article
  3. Evaluation ofJournal of pharmacy & bioallied sciences · 2024
    Article
  4. Antioxidant, Cytotoxicity, Antimicrobial Activity, andBiochemistry research international · 2023
    Article
  5. Review
  6. Review
  7. Review
  8. Evaluation of the Antimicrobial Effect of the Extracts of the Pods ofAdvances in pharmacological and pharmaceutical sciences · 2021
    Article
  9. Article
  10. Hydro-alcoholic Extract ofIranian journal of medical sciences · 2020
    Article
  11. Review
  12. Article
  13. Protective Effect of the Hexanic Extract ofAntioxidants (Basel, Switzerland) · 2019
    Article
  14. The effect ofBioscience reports · 2019
    Article
  15. Medicinal Plants in the Prevention and Treatment of Colon Cancer.Oxidative medicine and cellular longevity · 2019
    Review
  16. Article
  17. Review
  18. Effective Medicinal Plant in Cancer Treatment, Part 2: Review Study.Journal of evidence-based complementary & alternative medicine · 2017
    Review
  19. The Analgesic and Anti-Inflammatory Activity of Linum usitatissimum in Balb/c Mice.Journal of evidence-based complementary & alternative medicine · 2017
    Article
  20. A Review of the Antioxidant Activity of Celery ( Apium graveolens L).Journal of evidence-based complementary & alternative medicine · 2017
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Majid Asadi-SamaniStudent Research Committee, Medical Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran.
Wesam KootiStudent Research Committee, Kurdistan University of Medical Sciences, Sanandaj, Iran.
Elahe AslaniIslamic Azad University, Isfahan, Iran.
Hedayatollah ShirzadStudent Research Committee, Medical Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran shirzadeh@yahoo.com.
Shahrekord University of Medical Sciences · IRIslamic Azad University, Isfahan · IRKurdistan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Increase in cases of various cancers has encouraged the researchers to discover novel, more effective drugs from plant sources. This study is a review of medicinal plants in Iran with already investigated anticancer effects on various cell lines. Thirty-six medicinal plants alongside their products with anticancer effects as well as the most important plant compounds responsible for the plants' anticancer effect were introduced. Phenolic and alkaloid compounds were demonstrated to have anticancer effects on various cancers in most studies. The plants and their active compounds exerted anticancer effects by removing free radicals and antioxidant effects, cell cycle arrest, induction of apoptosis, and inhibition of angiogenesis. The investigated plants in Iran contain the compounds that are able to contribute effectively to fighting cancer cells. Therefore, the extract and active compounds of the medicinal plants introduced in this review article could open a way to conduct clinical trials on cancer and greatly help researchers and pharmacists develop new anticancer drugs.

Indexed as

Antineoplastic AgentsPlant ExtractsPlants, MedicinalAnimalsCell LineCell SurvivalHumansIranMiceAntineoplastic AgentsPlant Extractscancercytotoxicitymedicinal plantsphytochemicals

Identifiers

PMID26297173
OpenAlexW2316589265

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.