Evidence map›Paper›PMID 26296651›Full record

Trial reportNicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco2016

A Clustered Randomized Controlled Trial to Reduce Secondhand Smoke Exposure Among Nonsmoking Pregnant Women in Sichuan Province, China.

Lian Yang, Elisa K Tong, Zhengzhong Mao, Teh-Wei Hu, Anita H Lee

Open access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Exposure of second hand smoke in women and children: A narrative review.Journal of family medicine and primary care · 2021
    Review
  5. Article
  6. Disseminating a Smoke-free Homes Program to Low Socioeconomic Status Households in the United States Through 2-1-1: Results of a National Impact Evaluation.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2020
    Article
  7. Predictors of toxic metal exposures among US women of reproductive age.Journal of exposure science & environmental epidemiology · 2019
    Article
  8. Article
  9. Article
  10. Brief Counseling on Secondhand Smoke Exposure in Pregnant Women in Argentina and Uruguay.International journal of environmental research and public health · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 2 countries.

Lian YangDepartment of Health Economics, School of Administration, Chengdu University of Traditional Chinese Medicine, Chengdu, China;
Elisa K TongDepartment of Internal Medicine, University of California, Davis, Sacramento, CA; ektong@ucdavis.edu.
Zhengzhong MaoDepartment of Health Economics, Huaxi School of Public Health, University of Sichuan, Chengdu, China;
Teh-Wei HuSchool of Public Health, University of California, Berkeley, Berkeley, CA; Center for International Tobacco Control, Public Health Institute, Berkeley, CA.
Anita H LeeCenter for International Tobacco Control, Public Health Institute, Berkeley, CA.
Berkeley Public Health Division · USChengdu University of Traditional Chinese Medicine · CNPublic Health Clinical Center of Chengdu · CNPublic Health Institute · USUniversity of California, Davis · US

Funding

Research ProjectU54CA153499 · NCI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CHEN, MOON SHAO-CHUANG, CHOW, EDWARD A. · 2010 to 2015
$6.7M
Tobacco Control Policy Analysis & Intervention Evaluation in China and IndonesiaR01TW005938 · FIC · UNIVERSITY OF CALIFORNIA BERKELEY · PI HU, TEH-WEI · 2002 to 2011
$3.6M
Tobacco Control Policy Analysis & Intervention Evaluation in China and TanzaniaR01TW009295 · FIC · PUBLIC HEALTH INSTITUTE · PI HU, TEH-WEI · 2012 to 2016
$1.3M
FIC NIH HHS R01 TW009295FIC NIH HHS TW009295FIC NIH HHS TW05938NCI NIH HHS U54 CA153499
6 · The paper itself

Abstract

introductionNonsmoking pregnant women in China have significant exposure to secondhand smoke (SHS). Few interventions have focused on pregnant women reducing their SHS exposure.

methodsThis clustered randomized controlled trial, conducted at eight hospitals in Sichuan, China, compared a prenatal health education intervention with usual clinical care as a control. The primary outcome was self-reported "no SHS exposure" before and 3 months after birth. The intervention consisted of three large group educational sessions, standardized clinician advice, brief monthly follow-up calls, and educational materials and resources. A random sample of participants was biochemically validated before birth with hair nicotine, a long-term biomarker of smoke exposure.

resultsOverall, 1181 participants were randomized to intervention (n = 526) and control (n = 655) groups. More participants in the intervention group than the control group reported no SHS exposure 3 months after birth (Total: 77.9% vs. 52.6%, P < .001; Home: 81.2% vs. 53.3%, P < .001). The intervention group also had greater changes in improved smoke-free homes and SHS knowledge and attitudes. Controlling for covariates, the intervention group was less likely to report SHS exposure than the control group (Total: OR = 0.47, 95% CI = 0.31 to 0.71; Home: OR = 0.33, 95% CI = 0.21 to 0.53), and this effect was sustained 3 months after birth. The adjusted log concentration of hair nicotine for the intervention group decreased by 0.28 log µg/g more than the control group.

conclusionsOur smoke-free health education intervention for nonsmoking pregnant women significantly reduced SHS exposure before and after birth. This intervention model can become part of a standard protocol for the care of pregnant women in hospital settings.

Indexed as

Environmental ExposureHealth EducationPrenatal CareTobacco Smoke PollutionAdultChinaFemaleHairHumansNicotinePregnancyNicotineTobacco Smoke Pollution

Identifiers

PMID26296651
PMCPMC5942612
OpenAlexW2176457280

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.