Evidence map›Paper›PMID 26296521›Full record

ArticleJournal of behavioral medicine2016

Substance use, mental illness, and familial conflict non-negotiation among HIV-positive African-Americans: latent class regression and a new syndemic framework.

Allysha C Robinson, Amy R Knowlton, Andrea C Gielen, Joseph J Gallo

Open access · greenAbstract read
In one paragraph

Article in Journal of behavioral medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 3 pooled it
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 43 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Complex solutions for a complex problem: A meta-analysis of the efficacy of multiple-behavior interventions on change in outcomes related to HIV.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2021
    Pooled it
  4. Trial
  5. Article
  6. Smartphone and Wearable Device-Based Digital Phenotyping to Understand Substance use and its Syndemics.Journal of medical toxicology : official journal of the American College of Medical Toxicology · 2024
    Article
  7. Article
  8. Proposing a New Conceptual Syndemic Framework for COVID-19 Vaccine Hesitancy: A Narrative Review.International journal of environmental research and public health · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Allysha C RobinsonDepartment of Surgery, Brigham and Women's Hospital, Harvard Schools of Medicine and Public Health, Center for Surgery and Public Health, One Brigham Circle, 1620 Tremont Street, Suite BC-4-020-U, Boston, MA, 02134, USA. arobinson21@bwh.harvard.edu.
Amy R KnowltonDepartment of Health, Behavior and Society, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Andrea C GielenDepartment of Health, Behavior and Society, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Joseph J GalloDepartment of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Johns Hopkins University · US

Funding

Vaccine Response and Immunotherapeutics SWGP30AI094189 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Richard E. Chaisson · 2012 to 2026
$67.0M
Sustaining palliative care to drug users with HIV/AIDS & health disparitiesR01NR014050 · NINR · JOHNS HOPKINS UNIVERSITY · PI KNOWLTON, AMY · 2013 to 2017
$2.3M
Informal Caregiving & Medical Adherence Among HIV+ IDUsR01DA019413 · NIDA · JOHNS HOPKINS UNIVERSITY · PI KNOWLTON, AMY · 2006 to 2009
$2.2M
NIAID NIH HHS 1P30AI094189NIAID NIH HHS P30 AI094189NIDA NIH HHS R01 DA019413NINR NIH HHS R01 NR014050NINR NIH HHS R01 NR14050-01
6 · The paper itself

Abstract

We evaluated a synergistic epidemic (syndemic) of substance use, mental illness, and familial conflict non-negotiation among HIV-positive injection drug users (IDU). Baseline BEACON study data was utilized. Latent class analyses identified syndemic classes. These classes were regressed on sex, viral suppression, and acute care non-utilization. Females were hypothesized to have higher syndemic burden, and worse health outcomes than males. Nine percent of participants had high substance use/mental illness prevalence (Class 4); 23 % had moderate levels of all factors (Class 3); 25 % had high mental illness (Class 2); 43 % had moderate substance use/mental illness (Class 1; N = 331). Compared to Classes 1-3, Class 4 was mostly female (p < .05), less likely to achieve viral suppression, and more likely to utilize acute care (p < .05). Interventions should target African-American IDU females to improve their risk of negative medical outcomes. Findings support comprehensive syndemic approaches to HIV interventions, rather than singular treatment methods.

Indexed as

AdultBlack or African AmericanComorbidityFamily RelationsFemaleHIV InfectionsHumansMaleMental DisordersMiddle AgedSex FactorsSocioeconomic FactorsSubstance-Related DisordersUnited StatesAfrican-AmericansHealth disparitiesHealth services researchHIVInjection drug useSyndemic theoryViral suppression

Identifiers

PMID26296521
PMCPMC5125621
OpenAlexW1649637005

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.