ReviewDer Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen2015
[Complication management of infected osteosynthesis: Therapy algorithm for peri-implant infections].
Review in Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- Insights into treatment and outcome of fracture-related infection: a systematic literature review.Archives of orthopaedic and trauma surgery · 2019Pooled it
- POST-OSTEOSYNTHESIS INFECTION: EVALUATION OF A HISTORICAL COHORT AND DEVELOPMENT OF A CARE PROTOCOL.Acta ortopedica brasileira · 2025Article
- Bacterial pathogens and in-hospital mortality in revision surgery for periprosthetic joint infection of the hip and knee: analysis of 346 patients.European journal of medical research · 2023Observational
- Fracture Related Infections and Their Risk Factors for Treatment Failure-A Major Trauma Centre Perspective.Diagnostics (Basel, Switzerland) · 2022Article
- [Management of suspected early infection after osteosynthesis].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2021Article
- General treatment principles for fracture-related infection: recommendations from an international expert group.Archives of orthopaedic and trauma surgery · 2020Article
- Calculated parenteral initial treatment of bacterial infections: Bone and joint infections.GMS infectious diseases · 2020Article
- [Bone substitute materials as local drug carriers : Current status of substitutes of various origins].Der Orthopade · 2018Review
- [Antibiotic strategies in trauma surgery : Treatment of implant-associated infections].Der Unfallchirurg · 2017Review
- [Osteosynthesis-associated infections : Epidemiology, definition and diagnosis].Der Unfallchirurg · 2017Review
- [Implant-associated infections - Diagnostics].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2016Review
- [Infected osteosynthesis].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPeri-implant infections (PII) are one of the most frequent postoperative complications and require an individualized combined surgical and antibiotic management. In this review article we provide up to date scientific knowledge regarding the pathogenesis, classification, diagnosis and therapy of PII. The aim of this article is to explain the rational background and evidence of individual treatment options in order to elaborate concrete management recommendations. MATERIAL AND
methodsThe relevant scientific publications were critically reviewed for diagnostics, therapy and prevention of PII. Based on these data we present a combined surgical and antibiotic treatment algorithm for PII.
resultsWith a consistent interdisciplinary action high healing rates with eradication of PII can be achieved. In acute PII (< 6 weeks) the implant can normally be retained but this is dependent on the soft tissue conditions, while in chronic PII (> 6 weeks) the implant generally has to be removed in a one or two step exchange, depending on the soft tissue, bone defects and pathogen.
conclusionScientific knowledge and clinical data have led to new treatment algorithms for PII with improved outcome, decreased morbidity and shortened hospitalization. Systemic individualized antimicrobial therapy, radical septic and plastic surgery are the cornerstones for successful treatment of acute and chronic PII. The local use of antibiotics and application of bone substitute materials are other techniques for treatment but the exact importance must still be determined.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.