ArticlePediatric surgery international2015
Current clinical features in diagnosis and treatment for immaturity of ganglia in Japan: analysis from 10-year nationwide survey.
Article in Pediatric surgery international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Clinicopathologic features of allied disorders of Hirschsprung disease and status update.World journal of gastrointestinal surgery · 2025Review
- Conditions that mimic Hirschsprung's disease, but that are not Hirschsprung's disease.World journal of pediatric surgery · 2025Review
- Immaturity of Ganglia in Familial Onset: Three Cases of Twins and Their Brother.Surgical case reports · 2025Article
- Outcome of Santulli enterostomy in patients with immaturity of ganglia: single institutional experience from a case series.BMC surgery · 2022Article
- Comparison of Outcomes between Two Surgical Techniques for Patients with Intestinal Neuronal Dysplasia.Journal of immunology research · 2022Article
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7 authors.
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Abstract
backgroundTo identify the current clinical features in diagnosis and treatment for immaturity of ganglia (IG) in Japan, we retrospectively analyzed data for patients with IG from the nationwide surveys in Japan. This survey was performed by Japanese Study Group of allied disorders of Hirschsprung's disease (ADHD).
methodsIn primary research, data on totally 355 cases of ADHD were collected for 10 years (2001-2010). Fifteen patients were IG. All IG patients were confirmed by pathological examination. In secondary research, detail questionnaires were sent and collected.
resultsMale/female ratio was 9/6 and mean birth weight was 2474 g. All cases (100 %) were onset in neonatal period. Primary symptoms were abdominal distention (86.7 %), vomiting (53.3 %), and late egestion of meconium (26.7 %). An abnormal distention of intestine was recognized in 86.7 % on X-ray, and microcolon was recognized in 58.3 % on contrast enema. Caliber change was recognized in 58.3 % on laparotomy. An enterostomy was made in 13 patients (86.7 %), and an ileostomy was made in 69.2 %. Pathological diagnosis was performed in 100 %. Enterostomy was closed in 100 %.
conclusionsTotally, 15 definitive cases of IG in 10 years were collected and analyzed. All cases were onset in the neonatal period and almost all underwent enterostomy, but no mortalities occurred.
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