ArticlePloS one2015
Isolation of Tibet orbivirus, TIBOV, from Culicoides Collected in Yunnan, China.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Diversity and Host Blood Meal Analysis ofInsects · 2026Article
- Genomic, antigenic, and seroepidemiological characterization of an antigenically divergent Tibet orbivirus strain isolated fromFrontiers in microbiology · 2026Article
- Sustained circulation ofBiosafety and health · 2025Article
- Searching for potential Culicoides vectors of four orbiviruses in Yunnan Province, China.Parasites & vectors · 2025Article
- Whole-Genome Sequencing and Structure Study of Three Biting-Insect-Associated Viruses (Advances in virology · 2025Article
- Metavirome Identification and Pathogenicity Evaluation of Tibet Orbivirus in Pigs.Transboundary and emerging diseases · 2025Article
- Transcriptomic Investigation of the Virus Spectrum Carried by Midges in Border Areas of Yunnan Province.Viruses · 2024Article
- Evaluation of vector susceptibility inmSphere · 2024Article
- Genome and evolution of Tibet orbivirus, TIBOV (genusFrontiers in cellular and infection microbiology · 2024Article
- Nelson Bay Reovirus Isolated from Bats and Blood-Sucking Arthropods Collected in Yunnan Province, China.Microbiology spectrum · 2023Article
- Two putative novel serotypes of Tibet orbivirus isolated fromJournal of veterinary science · 2023Article
- Isolation and identification of Tete virus group (Frontiers in cellular and infection microbiology · 2023Article
- Recent Progress on Tick-Borne Animal Diseases of Veterinary and Public Health Significance in China.Viruses · 2022Review
- Characterization of a novel reassortment Tibet orbivirus isolated fromThe Journal of general virology · 2021Article
- Isolation of Tibet Orbivirus from Culicoides jacobsoni (Diptera, Ceratopogonidae) in China.Parasites & vectors · 2021Article
- Genomic analysis of putative novel serotypes of Tibet orbivirus isolated in Japan.Archives of virology · 2021Article
- Endemic and Emerging Arboviruses in Domestic Ruminants in East Asia.Frontiers in veterinary science · 2020Review
- Genetic diversity of the Yokose virus, XYBX1332, isolated from bats (Myotis daubentonii) in China.Virology journal · 2019Article
- Mosquito-Associated Viruses in China.Virologica Sinica · 2018Review
- Isolation of Tibet orbivirus from Culicoides and associated infections in livestock in Yunnan, China.Virology journal · 2017Article
Corrections and comments
- Erratum issued
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We isolated a novel virus strain (YN12246) from Culicoides spp. specimens collected at the China-Laos-Myanmar border in southern Yunnan Province. This virus had a cytopathic effect (CPE) on both insect cells (C6/36) and mammalian cells (BHK-21). Electron microscopy revealed the structure of the virions to be spherical with a diameter of 75 nm. Polyacrylamide gel analysis demonstrated that the viral genome consisted of 10 segments of double-stranded RNA (dsRNA), with a distribution pattern of 3-3-3-1. The coding sequences of 9 genome segments of YN12246 (Seg1, Seg3-Seg10) were obtained by high-throughput sequencing and Sanger sequencing. Comparisons of conserved genome segments 1 and 3 (Seg1 and Seg3), encoding the polymerase-VP1 and sub-core T2 protein, respectively, showed that YN12246 groups with the Culicoides-borne orbiviruses. The highest levels of sequence identity were detected between YN12246 and Tibet orbivirus (TIBOV), indicating that they belong to the same virus species (with amino acid identity of 98.8% and 96.4% for the polymerase and T2 protein, respectively). The data presented here confirm that YN12246 is a member of the TIBOV species, which was first isolated from mosquitoes in 2009. This is the first report of the isolation of TIBOV from Culicoides.
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