ReviewInternational journal of molecular sciences2015
Structural Features of the ATP-Binding Cassette (ABC) Transporter ABCA3.
Review in International journal of molecular sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 25 citations in OpenAlex.
- Assimilation of phthalate esters in bacteria.Applied microbiology and biotechnology · 2024Review
- Unraveling the Mechanism of Curculiginis Rhizoma in Suppressing Cisplatin Resistance in Non-Small Cell Lung Cancer: An Experimental Study.OncoTargets and therapy · 2024Article
- Novel insights into congenital surfactant dysfunction disorders by in silico analysis of ABCA3 proteins.World journal of pediatrics : WJP · 2023Article
- Decision tree algorithm predicts hepatocellular carcinoma among chronic hepatitis C patients following viral eradication.American journal of cancer research · 2023Article
- Cryo-EM structures of the human surfactant lipid transporter ABCA3.Science advances · 2022Article
- Structure-Based Understanding of ABCA3 Variants.International journal of molecular sciences · 2021Article
- Genetic disorders of the surfactant system: focus on adult disease.European respiratory review : an official journal of the European Respiratory Society · 2021Article
- Research Progress on the Functions and Mechanism of circRNA in Cisplatin Resistance in Tumors.Frontiers in pharmacology · 2021Review
- Functional Genomics ofAmerican journal of respiratory cell and molecular biology · 2020Article
- Neonatal respiratory failure due to novel compound heterozygous mutations in the ABCA3 lipid transporter.Cold Spring Harbor molecular case studies · 2020Article
- ATP-binding cassette transporter A1: A promising therapy target for prostate cancer.Molecular and clinical oncology · 2018Article
- Variants of the ABCA3 gene might contribute to susceptibility to interstitial lung diseases in the Chinese population.Scientific reports · 2017Article
- Examining the role of ABC lipid transporters in pulmonary lipid homeostasis and inflammation.Respiratory research · 2017Review
- Shenmai injection enhances the cytotoxicity of chemotherapeutic drugs against colorectal cancers via improving their subcellular distribution.Acta pharmacologica Sinica · 2017Article
- The translational expression of ABCA2 and ABCA3 is a strong prognostic biomarker for multidrug resistance in pediatric acute lymphoblastic leukemia.OncoTargets and therapy · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this review we reported and discussed the structural features of the ATP-Binding Cassette (ABC) transporter ABCA3 and how the use of bioinformatics tools could help researchers to obtain a reliable structural model of this important transporter. In fact, a model of ABCA3 is still lacking and no crystallographic structures (of the transporter or of its orthologues) are available. With the advent of next generation sequencing, many disease-causing mutations have been discovered and many more will be found in the future. In the last few years, ABCA3 mutations have been reported to have important pediatric implications. Thus, clinicians need a reliable structure to locate relevant mutations of this transporter and make genotype/phenotype correlations of patients affected by ABCA3-related diseases. In conclusion, we strongly believe that the model preliminarily generated by these novel bioinformatics tools could be the starting point to obtain more refined models of the ABCA3 transporter.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.