Evidence map›Paper›PMID 26295242›Full record

ReviewMarine drugs2015

Are the Traditional Medical Uses of Muricidae Molluscs Substantiated by Their Pharmacological Properties and Bioactive Compounds?

Kirsten Benkendorff, David Rudd, Bijayalakshmi Devi Nongmaithem, Lei Liu, Fiona Young, Vicki Edwards, Cathy Avila, Catherine A Abbott

Abstract readReview
In one paragraph

Review in Marine drugs, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Sea conch (Food science & nutrition · 2024
    Article
  2. Review
  3. Review
  4. Article
  5. Pharmaceutical biology · 2022
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Review
  14. The first complete mitochondrial genome ofMitochondrial DNA. Part B, Resources · 2019
    Article
  15. Article
  16. Bromoperoxidase ProducingMarine drugs · 2019
    Article
  17. Article
  18. Review
  19. Antidiabetic Activity and Chemical Composition ofEvidence-based complementary and alternative medicine : eCAM · 2018
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kirsten BenkendorffMarine Ecology Research Centre, School of Environment, Science and Engineering, Southern Cross University, G.P.O. Box 157, Lismore, NSW 2480, Australia. Kirsten.benkendorff@scu.edu.au.
David RuddSchool of Biological Sciences, Flinders University, G.P.O. Box 2100, Adelaide 5001, Australia. david.rudd@flinders.edu.au.
Bijayalakshmi Devi NongmaithemMarine Ecology Research Centre, School of Environment, Science and Engineering, Southern Cross University, G.P.O. Box 157, Lismore, NSW 2480, Australia. n.nongmaithem.10@student.scu.edu.au.
Lei LiuSouthern Cross Plant Science, Southern Cross University, G.P.O. Box 157, Lismore, NSW 2480, Australia. ben.liu@scu.edu.au.
Fiona YoungMedical Biotechnology, Flinders University, G.P.O. Box 2100, Adelaide 5001, Australia. Fiona.young@scu.edu.au.
Vicki EdwardsMedical Biotechnology, Flinders University, G.P.O. Box 2100, Adelaide 5001, Australia. Vicki.Edwards@bioinnovationsa.com.au.
Cathy AvilaSchool of Health Science, Southern Cross University, G.P.O. Box 157, Lismore, NSW 2480, Australia. Cathy.avila@scu.edu.au.
Catherine A AbbottSchool of Biological Sciences, Flinders University, G.P.O. Box 2100, Adelaide 5001, Australia. cathy.abbott@flinders.edu.au.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Marine molluscs from the family Muricidae hold great potential for development as a source of therapeutically useful compounds. Traditionally known for the production of the ancient dye Tyrian purple, these molluscs also form the basis of some rare traditional medicines that have been used for thousands of years. Whilst these traditional and alternative medicines have not been chemically analysed or tested for efficacy in controlled clinical trials, a significant amount of independent research has documented the biological activity of extracts and compounds from these snails. In particular, Muricidae produce a suite of brominated indoles with anti-inflammatory, anti-cancer and steroidogenic activity, as well as choline esters with muscle-relaxing and pain relieving properties. These compounds could explain some of the traditional uses in wound healing, stomach pain and menstrual problems. However, the principle source of bioactive compounds is from the hypobranchial gland, whilst the shell and operculum are the main source used in most traditional remedies. Thus further research is required to understand this discrepancy and to optimise a quality controlled natural medicine from Muricidae.

Indexed as

AnimalsAnti-Inflammatory AgentsAntineoplastic AgentsBiological FactorsHumansMedicine, TraditionalMolluscaSnailsAnti-Inflammatory AgentsAntineoplastic AgentsBiological Factorscholine estersethnomedicineindolesmarine natural productswhelk

Identifiers

PMID26295242
PMCPMC4557022

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.