ArticleEvidence-based complementary and alternative medicine : eCAM2015
Acupuncture for Functional Dyspepsia: A Single Blinded, Randomized, Controlled Trial.
Article in Evidence-based complementary and alternative medicine : eCAM, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 6 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Efficacy and safety of acupuncture for functional dyspepsia: an updated meta-analysis of randomized controlled trials.Frontiers in medicine · 2026Pooled it
- Adjunctive acupuncture for sepsis-associated acute gastrointestinal injury: a systematic review, meta-analysis, and exploratory Bayesian network meta-analysis.Frontiers in medicine · 2026Pooled it
- Efficacy and safety of acupuncture for postoperative gastroparesis syndrome: a systematic review and meta-analysis.Frontiers in medicine · 2024Pooled it
- Efficacy of acupuncture for anxiety and depression in functional dyspepsia: A systematic review and meta-analysis.PloS one · 2024Pooled it
- Acupuncture for emotional symptoms in patients with functional gastrointestinal disorders: A systematic review and meta-analysis.PloS one · 2022Pooled it
- Effects and mechanisms of acupuncture and electroacupuncture for functional dyspepsia: A systematic review.World journal of gastroenterology · 2020Pooled it
- Trial
- Trial
- Electroacupuncture alleviates functional dyspepsia by modulating the vagus nerve to regulate duodenal microbiota and suppress TWEAK/Fn14/NF-κB and arachidonic acid metabolic pathways.Frontiers in immunology · 2026Article
- Non-invasive neuromodulation: an emerging intervention for visceral pain in gastrointestinal disorders.Bioelectronic medicine · 2023Review
- Effects of acupuncture on functional gastrointestinal disorders: special effects, coeffects, synergistic effects in terms of single or compatible acupoints.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2023Review
- Electroacupuncture modulates the intestinal microecology to improve intestinal motility in spinal cord injury rats.Microbial biotechnology · 2022Article
- Design characteristics of comparative effectiveness trials for the relief of symptomatic dyspepsia: A systematic review.Integrative medicine research · 2021Review
- Effects of electroacupuncture on stress-induced gastric dysrhythmia and mechanisms involving autonomic and central nervous systems in functional dyspepsia.American journal of physiology. Regulatory, integrative and comparative physiology · 2020Article
- The Effects of Low-Dose and High-Dose Decoctions of Fructus aurantii in a Rat Model of Functional Dyspepsia.Medical science monitor : international medical journal of experimental and clinical research · 2020Article
- Efficacy Comparison of Different Acupuncture Treatments for Functional Dyspepsia: A Systematic Review with Network Meta-Analysis.Evidence-based complementary and alternative medicine : eCAM · 2020Review
- Electroacupuncture at ST36 modulates gastric motilityWorld journal of gastroenterology · 2019Article
- EA at PC6 Promotes Gastric Motility: Role of Brainstem Vagovagal Neurocircuits.Evidence-based complementary and alternative medicine : eCAM · 2019Article
- Brain-Gut Axis Modulation of Acupuncture in Functional Dyspepsia: A Preliminary Resting-State fcMRI Study.Evidence-based complementary and alternative medicine : eCAM · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In order to investigate the therapeutic potential of acupuncture on patients with functional dyspepsia (FD), patients were randomized to receive acupuncture at classic acupoints with manipulations (treatment group) versus acupuncture at nonacupoints without manipulation (control group) once every other day, three times a week, for one month and were followed up for three months. The primary outcomes included dyspeptic symptoms, quality of life, and mental status. The secondary outcomes included the fasting serum gastrin concentration, and frequency and propagation velocity of gastric slow waves. Sixty patients with FD were included, among whom, four dropped out. After one month's treatment, patients with FD showed significant improvements in primary (in both groups) and secondary (in the eight patients of the treatment group) outcomes as compared with baseline (P = 0.0078 to <0.0001); treatment group has better outcomes in all primary outcome measures (P < 0.0001 except for SDS (P = 0.0005)). Improvements on dyspeptic symptoms persist during follow-up (better in the treatment group). Acupuncture with manual manipulation had better effects on improving dyspeptic symptoms, mental status, and quality of life in patients with FD. These effects may be related to the increased frequency and propagation speed of gastric slow waves and serum gastrin secretion.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.