Evidence map›Paper›PMID 26294923›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2015

Electroacupuncture versus Moxibustion for Irritable Bowel Syndrome: A Randomized, Parallel-Controlled Trial.

Yin Shi, Yue-Hua Chen, Xiao-Jun Yin, An-Qi Wang, Xing-Kui Chen, Jin-Hua Lu, Rong Ji, Chun-Hui Bao, Jie Sun, Ji-Meng Zhao and 1 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Yin ShiDepartment of Medical Clinic, Yueyang Chinese and Western Medicine Integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China.
Yue-Hua ChenDepartment of Gastroenterology, Jinhua Municipal Central Hospital, Jinhua 321000, China.
Xiao-Jun YinDepartment of Medical Clinic, Yueyang Chinese and Western Medicine Integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China.
An-Qi WangDepartment of Medical Clinic, Yueyang Chinese and Western Medicine Integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China.
Xing-Kui ChenDepartment of Acupuncture and Moxibustion, Jinhua Municipal Central Hospital, Jinhua 321000, China.
Jin-Hua LuDepartment of Medical Imaging, Jinhua Municipal Central Hospital, Jinhua 321000, China.
Rong JiDepartment of Medical Clinic, Yueyang Chinese and Western Medicine Integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China.
Chun-Hui BaoDepartment of Medical Clinic, Yueyang Chinese and Western Medicine Integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China.
Jie SunDepartment of Medical Clinic, Yueyang Chinese and Western Medicine Integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China.
Ji-Meng ZhaoDepartment of Medical Clinic, Yueyang Chinese and Western Medicine Integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China.
Huan-Gan WuDepartment of Medical Clinic, Yueyang Chinese and Western Medicine Integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China.
Yueyang Hospital · CNJinhua Central Hospital · CNShanghai University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective. To compare the impacts of electroacupuncture (EA) and mild moxibustion (Mox) on patients with irritable bowel syndrome (IBS). Method. Eighty-two IBS patients were randomly allocated into EA group (n = 41) and Mox group (n = 41) and received corresponding interventions for four weeks. Before and after the treatment, the Visual Analogue Scale for Irritable Bowel Syndrome (VAS-IBS) was used to evaluate the gastrointestinal symptoms and mental well-being; and the expression of serotonin (5-hydroxytryptamine, 5-HT), 5-HT3 receptor (5-HT3R), and 5-HT4 receptor (5-HT4R) in sigmoid mucosal tissue were detected. Results. Both EA and Mox can radically improve the total VAS-IBS score (P < 0.05), and EA was found to be more effective in ameliorating the symptom of constipation, while Mox was found to be more effective in ameliorating the symptom of diarrhoea. The abnormal expressions of 5-HT, 5-HT3R, and 5-HT4R in both groups were significantly improved after the treatments (all P < 0.05), and EA was superior to Mox in regulating the abnormally decreased 5-HT4R expression in IBS patients with constipation (P < 0.05). Conclusion. Electroacupuncture and mild moxibustion were both effective in improving IBS symptoms and modulate abnormal expressions of 5-HT, 5-HT3R, and 5-HT4R in the colonic tissue.

Identifiers

PMID26294923
PMCPMC4534607
OpenAlexW1553348985

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.