Evidence map›Paper›PMID 26294728›Full record

ArticleHaematologica2015

Ligand-induced STAT3 signaling increases at relapse and is associated with outcome in pediatric acute myeloid leukemia: a report from the Children's Oncology Group.

Alexandra M Stevens, Marcos J Ruiz, Robert B Gerbing, Todd A Alonzo, Alan S Gamis, Michele S Redell

Abstract readLetterMulticenter Study
In one paragraph

Article in Haematologica, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alexandra M StevensDivision of Pediatric Hematology/Oncology, Baylor College of Medicine, Houston, TX, USA amsteven@txch.org.
Marcos J RuizDivision of Pediatric Hematology/Oncology, Baylor College of Medicine, Houston, TX, USA.
Robert B GerbingChildren's Oncology Group, Monrovia, CA, USA.
Todd A AlonzoDepartment of Preventive Medicine, University of Southern California, Los Angeles, CA, USA.
Alan S GamisChildren's Mercy Hospitals and Clinics, Kansas City, MO, USA.
Michele S RedellDivision of Pediatric Hematology/Oncology, Baylor College of Medicine, Houston, TX, USA.

Funding

COG SDMC - Statistics CoreU10CA180899 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI TODD A ALONZO · 2014 to 2026
$132.8M
Tumor BiologyP30CA125123 · NCI · BAYLOR COLLEGE OF MEDICINE · PI Michael M Ittmann · 2007 to 2026
$73.9M
Virology CoreP30AI036211 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI BUTEL, JANET S · 1994 to 2015
$21.7M
PEDIATRIC ONCOLOGY CLINICAL RESEARCH TRAINING PROGRAMK12CA090433 · NCI · BAYLOR COLLEGE OF MEDICINE · PI CARL E ALLEN, Donald W. Parsons · 2002 to 2026
$18.5M
Support for Human Specimen Banking in NCI-Supported Cancer Clinical TrialsU24CA114766 · NCI · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI RAMIREZ MILAN, NILSA DEL CARMEN · 2005 to 2014
$14.5M
Using Stat3 Signaling Profiles to Understand Chemotherapy Resistance in AMLR01CA175026 · NCI · BAYLOR COLLEGE OF MEDICINE · PI REDELL, MICHELE S. · 2014 to 2018
$2.0M
Stat3 Isoforms in Maturation and Survival of Normal and Malignant Myeloid CellsK08HL085018 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI REDELL, MICHELE S. · 2008 to 2012
$641k
BD Biosciences Special Order LSRIIS10RR024574 · NCRR · BAYLOR COLLEGE OF MEDICINE · PI LUMPKIN, ELLEN A · 2009 to 2009
$430k
NCI NIH HHS 1U10CA180899-01NCI NIH HHS K12 CA090433NCI NIH HHS K12CA090433NCI NIH HHS P30 CA125123NCI NIH HHS R01 CA175026NCI NIH HHS U10 CA180899NCI NIH HHS U24CA114766NCRR NIH HHS S10 RR024574NHLBI NIH HHS K08HL085018NIAID NIH HHS P30 AI036211
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Signal TransductionAdolescentChildChild, PreschoolFemaleHumansInfantLeukemia, Myeloid, AcuteMaleRecurrenceSTAT3 Transcription FactorSTAT3 protein, humanSTAT3 Transcription Factoracute myeloid leukemialigand stimulationpediatricrelapseSTAT3

Identifiers

PMID26294728
PMCPMC4666340

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.