Evidence map›Paper›PMID 26294723›Full record

Trial reportHaematologica2015

A phase II multi-center trial of pentostatin plus cyclophosphamide with ofatumumab in older previously untreated chronic lymphocytic leukemia patients.

Alessandra Tedeschi, Davide Rossi, Marina Motta, Giulia Quaresmini, Marianna Rossi, Marta Coscia, Antonella Anastasia, Fausto Rossini, Agostino Cortelezzi, Guido Nador and 12 more

Abstract readClinical Trial, Phase IIILetterMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Haematologica, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Emerging Role of Purine Metabolizing Enzymes in Brain Function and Tumors.International journal of molecular sciences · 2018
    Review
  6. The Inside Story of Adenosine.International journal of molecular sciences · 2018
    Review
  7. Review
  8. Current Treatment of Chronic Lymphocytic Leukemia.Current treatment options in oncology · 2017
    Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Alessandra TedeschiDept. of Haematology, Niguarda Cancer Center, Milan, Italy alessandra.tedeschi@ospedaleniguarda.it.
Davide RossiDivision of Haematology, Department of Translational Medicine, Amedeo Avogadro University of EasternPiedmont, Novara, Italy.
Marina MottaDept. of Haematology, Spedali Civili, Brescia, Italy.
Giulia QuaresminiHaematology and Bone MarrowTransplant Unit, Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Italy.
Marianna RossiDept. of HaematologyOncology, Fondazione IRCCS Policlinico San Matteo &University of Pavia, Italy.
Marta CosciaDivision of Haematology, University of Torino, A.O. Città della Salute e della Scienza di Torino, Italy.
Antonella AnastasiaDept. of Haematology, Humanitas Cancer Center, Rozzano, Italy.
Fausto RossiniHaematology Unit, Ospedale San Gerardo, Monza, Italy.
Agostino CortelezziDept. of Haematology and BMT Unit, University of Milan, Ospedale Maggiore, Italy.
Guido NadorInternal Medicine Dept., Hospital of Legnano, Italy.
Lydia ScarfòDept. of Onco-Haematology, University Vita-Salute San Raffaele, Milan, Italy.
Roberto CairoliDept. of Internal Medicine, Ospedale Valduce, Como, Italy.
Anna Maria FrustaciDept. of Haematology, Niguarda Cancer Center, Milan, Italy.
Daniela DalceggioDept. of Haematology, Spedali Civili, Brescia, Italy.
Paola PicardiDept. of Haematology, Niguarda Cancer Center, Milan, Italy.
Lorenzo De PaoliDivision of Haematology, Department of Translational Medicine, Amedeo Avogadro University of EasternPiedmont, Novara, Italy.
Ester OrlandiDept. of HaematologyOncology, Fondazione IRCCS Policlinico San Matteo &University of Pavia, Italy.
Alessandro RambaldiHaematology and Bone MarrowTransplant Unit, Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Italy.
Massimo MassaiaDivision of Haematology, University of Torino, A.O. Città della Salute e della Scienza di Torino, Italy.
Gianluca GaidanoDivision of Haematology, Department of Translational Medicine, Amedeo Avogadro University of EasternPiedmont, Novara, Italy.
Marco MontilloDept. of Haematology, Niguarda Cancer Center, Milan, Italy.
Rete Ematologica Lombarda–CLL Workgroup

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAgedAged, 80 and overAntineoplastic Combined Chemotherapy ProtocolsCyclophosphamideFemaleFollow-Up StudiesHumansLeukemia, Lymphocytic, Chronic, B-CellMaleMiddle AgedPentostatinCyclophosphamidePentostatinchronic lymphocytic leukemiacyclophosphamideelderlyofatumumabpentostatin

Identifiers

PMID26294723
PMCPMC4666341

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.