ArticleAJNR. American journal of neuroradiology2015
Fusion of Freehand SPECT and Ultrasound to Perform Ultrasound-Guided Fine-Needle Aspiration Cytology of Sentinel Nodes in Head and Neck Cancer.
Article in AJNR. American journal of neuroradiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- LiDAR-registered freehand SPECT combined with NIR-fluorescence enables spatial localisation of tracer-avid inguinal lymph nodes: A clinical feasibility study.European journal of nuclear medicine and molecular imaging · 2026Article
- Limited Sensitivity of Ultrasound-Guided Fine-Needle Aspiration Cytology for Occult Nodal Metastases in Early-Stage Oral Squamous Cell Carcinoma.Head & neck · 2026Article
- Evaluating the Diagnosis of Cervical Lymph Node Metastasis In Oral Squamous Cell Carcinoma by Clinicopathologic Investigation.Journal of pharmacy & bioallied sciences · 2025Article
- Simultaneous Identification of Tc-99m-Sestamibi-Positive Autonomous Thyroid Adenoma and Adjacent F-18-Ethylcholine-Positive Parathyroid Adenoma in Patient with Graves' Disease Using Real-Time Ultrasound Fusion Imaging.Diagnostics (Basel, Switzerland) · 2025Article
- The potential of the Crystal Cam handheld gamma-camera for preoperative and intraoperative sentinel lymph node localization in early-stage oral cancer.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023Article
- Feasibility and Performance of Free-Hand Single-Photon Computed Tomography/Ultrasonography for Preoperative Parathyroid Adenoma Localization: A Pilot Study.Diagnostics (Basel, Switzerland) · 2023Article
- The role of magnetic resonance imaging and computed tomography in oral squamous cell carcinoma patients' preoperative staging.Frontiers in oncology · 2023Article
- Article
- A Systematic Review of Oral Biopsies, Sample Types, and Detection Techniques Applied in Relation to Oral Cancer Detection.Biotech (Basel (Switzerland)) · 2022Review
- Sentinel Node Identification in Melanoma: Current Clinical Impact, New Emerging SPECT Radiotracers and Technological Advancements. An Update of the Last Decade.Current radiopharmaceuticals · 2020Review
- Introducing navigation during melanoma-related sentinel lymph node procedures in the head-and-neck region.EJNMMI research · 2017Article
- Hybrid intraoperative imaging techniques in radioguided surgery: present clinical applications and future outlook.Clinical and translational imaging · 2017Review
- Fusion of freehand SPECT and ultrasound: First experience in preoperative localization of sentinel lymph nodes.European journal of nuclear medicine and molecular imaging · 2016Article
- Crossing technological frontiers in radioguided intervention.European journal of nuclear medicine and molecular imaging · 2016Article
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4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
background and purposeCriteria for ultrasound-guided fine-needle aspiration cytology (USgFNAC) for the detection of occult lymph node metastasis in patients with clinically negative head and neck cancer are based on the morphology of cervical lymph nodes. To improve the selection of lymph nodes for USgFNAC, we examined the feasibility of fused freehand single-photon emission tomography ultrasound-guided fine-needle cytology (freehand SPECT-USgFNAC) of sentinel nodes in patients with early stage oral and head and neck skin cancer. MATERIALS AND
methodsSix patients with early-stage head and neck cancer (4 oral and 2 head and neck skin cancers) and a clinically negative neck who were scheduled for transoral or local excision and a sentinel node procedure underwent USgFNAC and freehand SPECT-USgFNAC preoperatively.
resultsAll freehand SPECT sonographic examinations were technically successful in terms of identifying sentinel nodes. All aspirates of sentinel nodes obtained by freehand SPECT-USgFNAC contained substantial radioactivity, confirming puncture of the sentinel nodes. USgFNAC evaluated 13 lymph nodes; freehand SPECT-USgFNAC, 19 nodes; and sentinel node biopsy, 13 nodes. Three sentinel nodes were histopathologically positive and were selected for aspiration cytology by freehand SPECT-USgFNAC, but not by conventional ultrasound. The cytologic examination findings of the aspirations were negative or inconclusive.
conclusionsFreehand SPECT ultrasound can identify sentinel nodes and could potentially improve USgFNAC in patients with head and neck cancer by better selection of lymph nodes at highest risk of having metastases (sentinel nodes), but its sensitivity is limited by sampling error and insufficient aspirated material for cytology.
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