Evidence map›Paper›PMID 26294401›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2016

Retroviral Transduction of T Cells and T Cell Precursors.

Amie Simmons, José Alberola-Ila

Abstract read
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Clinical translation of epigenome editing technologies.Current opinion in biomedical engineering · 2026
    Article
  2. Article
  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Amie SimmonsImmunobiology and Cancer Program, Oklahoma Medical Research Foundation, 825 NE 13th Street, MS 29, Oklahoma City, OK, 73104, USA.
José Alberola-Ila

Funding

Understanding connective tissue development and disease with PDGFR-driven..... P20GM103636 · NIGMS · OKLAHOMA MEDICAL RESEARCH FOUNDATION · PI THOMPSON, LINDA F · 2013 to 2023
$26.9M
Hematopoietic Stem Cell SenescenceR01HL107138 · NHLBI · OKLAHOMA MEDICAL RESEARCH FOUNDATION · PI ALBEROLA-ILA, JOSE, KINCADE, PAUL WAYNE · 2010 to 2013
$1.6M
NHLBI NIH HHS R01 HL107138NIGMS NIH HHS P20 GM103636
6 · The paper itself

Abstract

Transduction of lymphoid progenitors with retroviral or lentiviral vectors is a powerful experimental strategy to tease out the role of a gene or pathway in T cell development via gain-of-function or loss-of-function strategies. Here we discuss different approaches to use this powerful technology, and present some protocols that we use to transduce murine HSCs, thymocytes, and lymphoid cell lines with these viral vectors.

Indexed as

Transduction, GeneticAnimalsCell LineGenetic VectorsHumansMicePrecursor Cells, T-LymphoidRetroviridaeT-Lymphocytes

Identifiers

PMID26294401
PMCPMC5562401

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.