Evidence map›Paper›PMID 26294183›Full record

ArticleCurrent biology : CB2015

Vision Science: Can Rhodopsin Cure Blindness?

Russell N Van Gelder, Kuldeep Kaur

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Current biology : CB, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Russell N Van GelderDepartment of Ophthalmology, University of Washington School of Medicine, Seattle, WA 98104, USA; Department of Biological Structure, University of Washington School of Medicine, Seattle, WA 98104, USA; Department of Pathology, University of Washington School of Medicine, Seattle, WA 98104, USA. Electronic address: russvg@uw.edu.
Kuldeep KaurDepartment of Ophthalmology, University of Washington School of Medicine, Seattle, WA 98104, USA.
University of Washington · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Outer retinal degeneration is the leading cause of blindness in the developed world. A new study now demonstrates that ectopic expression of human rhodopsin in the inner retina, mediated by viral gene therapy, can restore light sensitivity and some vision to mice blind from outer retinal degeneration.

Indexed as

Ectopic Gene ExpressionAnimalsHumansRetinal DegenerationRhodopsinRhodopsin

Identifiers

PMID26294183
OpenAlexW1589232394

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.