ReviewThe international journal of cardiovascular imaging2016
Advanced MRI for carotid plaque imaging.
Review in The international journal of cardiovascular imaging, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 54 citations in OpenAlex.
- Trial
- Noninvasive Assessment of Arterial Compliance and Lumen Pressure in Human Carotid Arteries Using Physics-Informed Neural Networks and Ultrasound Imaging: A Clinical Feasibility Study.Research square · 2026Article
- Integrating MRI radiomics with novel fluid-based texture features (GLFZM) to predict atherothrombotic stroke risk.Radiological physics and technology · 2025Article
- Visceral adipose tissue and hepatic fat as determinants of carotid atherosclerosis.Communications medicine · 2025Article
- Imaging of Carotid Stenosis: Where Are We Standing? Comparison of Multiparametric Ultrasound, CT Angiography, and MRI Angiography, with Recent Developments.Diagnostics (Basel, Switzerland) · 2024Review
- Predictive values of carotid high-resolution magnetic resonance imaging for large embolus shedding in carotid artery stenting.Turkish journal of medical sciences · 2022Article
- Reassessing the Carotid Artery Plaque "Rim Sign" on CTA: A New Analysis with Histopathologic Confirmation.AJNR. American journal of neuroradiology · 2022Article
- Black-Blood Contrast in Cardiovascular MRI.Journal of magnetic resonance imaging : JMRI · 2022Review
- Deep learning-based hemodynamic prediction of carotid artery stenosis before and after surgical treatments.Frontiers in physiology · 2022Article
- Emerging Role of Carotid MRI for Personalized Ischemic Stroke Risk Prediction in Patients With Carotid Artery Stenosis.Frontiers in neurology · 2021Review
- Carotid Artery Plaque Identification and Display System (MRI-CAPIDS) Using Opensource Tools.Diagnostics (Basel, Switzerland) · 2020Article
- Imaging of inflammatory cellular protagonists in human atherosclerosis: a dual-isotope SPECT approach.European journal of nuclear medicine and molecular imaging · 2020Article
- Plaque imaging volume analysis: technique and application.Cardiovascular diagnosis and therapy · 2020Review
- Carotid plaque imaging and the risk of atherosclerotic cardiovascular disease.Cardiovascular diagnosis and therapy · 2020Review
- Evaluating cervical artery dissections in young adults: a comparison study between high-resolution MRI and CT angiography.The international journal of cardiovascular imaging · 2020Article
- Cardiovascular risk scoring and magnetic resonance imaging detected subclinical cerebrovascular disease.European heart journal. Cardiovascular Imaging · 2020Article
- Serum insulin levels are associated with vulnerable plaque components in the carotid artery: the Rotterdam Study.European journal of endocrinology · 2020Article
- Coronary CT Angiography and Carotid MRI Improve Phenotyping of Disease Extent Compared with ACC/AHA Risk Score Alone.Radiology. Cardiothoracic imaging · 2020Article
- Effect of cigarette smoking on carotid artery atherosclerosis: a community-based cohort study.Heart and vessels · 2020Article
- Imaging the carotid atherosclerotic plaque.Vascular biology (Bristol, England) · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
Atherosclerosis is the ubiquitous underling pathological process that manifests in heart attack and stroke, cumulating in the death of one in three North American adults. High-resolution magnetic resonance imaging (MRI) is able to delineate atherosclerotic plaque components and total plaque burden within the carotid arteries. Using dedicated hardware, high resolution images can be obtained. Combining pre- and post-contrast T1, T2, proton-density, and magnetization-prepared rapid acquisition gradient echo weighted fat-saturation imaging, plaque components can be defined. Post-processing software allows for semi- and fully automated quantitative analysis. Imaging correlation with surgical specimens suggests that this technique accurately differentiates plaque features. Total plaque burden and specific plaque components such as a thin fibrous cap, large fatty or necrotic core and intraplaque hemorrhage are accepted markers of neuroischemic events. Given the systemic nature of atherosclerosis, emerging science suggests that the presence of carotid plaque is also an indicator of coronary artery plaque burden, although the preliminary data primarily involves patients with stable coronary disease. While the availability and cost-effectiveness of MRI will ultimately be important determinants of whether carotid MRI is adopted clinically in cardiovascular risk assessment, the high accuracy and reliability of this technique suggests that it has potential as an imaging biomarker of future risk.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.