Evidence map›Paper›PMID 26293231›Full record

ArticleInternational journal of obesity (2005)2015

Adenovirus 36 DNA in human adipose tissue.

E Ponterio, R Cangemi, S Mariani, G Casella, A De Cesare, F M Trovato, A Garozzo, L Gnessi

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In one paragraph

Article in International journal of obesity (2005), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 28 citations in OpenAlex.

  1. Human Adenovirus 36 Antibodies in Horses with Different Metabolic Statuses.Animals : an open access journal from MDPI · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

E PonterioDepartment of Experimental Medicine, Section of Medical Pathophysiology Food Science and Endocrinology, Sapienza University of Rome, Rome, Italy.
R CangemiDepartment of Internal Medicine and Medical Specialties, Sapienza University of Rome, Rome, Italy.
S MarianiDepartment of Experimental Medicine, Section of Medical Pathophysiology Food Science and Endocrinology, Sapienza University of Rome, Rome, Italy.
G CasellaDepartment of Surgical Sciences, Sapienza University of Rome, Rome, Italy.
A De CesareDepartment of Surgery 'Pietro Valdoni', Sapienza University of Rome, Rome, Italy.
F M TrovatoDepartment of Clinical and Experimental Medicine, Internal Medicine Division, University of Catania, Catania, Italy.
A GarozzoDepartment of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy.
L GnessiDepartment of Experimental Medicine, Section of Medical Pathophysiology Food Science and Endocrinology, Sapienza University of Rome, Rome, Italy.
Sapienza University of Rome · ITUniversity of Catania · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent studies have suggested a possible correlation between obesity and adenovirus 36 (Adv36) infection in humans. As information on adenoviral DNA presence in human adipose tissue are limited, we evaluated the presence of Adv36 DNA in adipose tissue of 21 adult overweight or obese patients. Total DNA was extracted from adipose tissue biopsies. Virus detection was performed using PCR protocols with primers against specific Adv36 fiber protein and the viral oncogenic E4orf1 protein nucleotide sequences. Sequences were aligned with the NCBI database and phylogenetic analyses were carried out with MEGA6 software. Adv36 DNA was found in four samples (19%). This study indicates that some individuals carry Adv36 in the visceral adipose tissue. Further studies are needed to determine the specific effect of Adv36 infection on adipocytes, the prevalence of Adv36 infection and its relationship with obesity in the perspective of developing a vaccine that could potentially prevent or mitigate infection.

Indexed as

AdenoviridaeAdenoviruses, HumanAdenovirus Infections, HumanAdultBody Mass IndexDNA, ViralFemaleHumansIntra-Abdominal FatItalyMaleMiddle AgedObesityPhylogenyDNA, Viral

Identifiers

PMID26293231
OpenAlexW1799804931

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.