Evidence map›Paper›PMID 26292295›Full record

ArticleJournal of clinical microbiology2015

Recurrent Methicillin-Resistant Staphylococcus aureus Cutaneous Abscesses and Selection of Reduced Chlorhexidine Susceptibility during Chlorhexidine Use.

Ryan C Johnson, Carey D Schlett, Katrina Crawford, Jeffrey B Lanier, D Scott Merrell, Michael W Ellis

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Journal of clinical microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 26 citations in OpenAlex.

  1. Trial
  2. Article
  3. Increasing usage of chlorhexidine in health care settings: blessing or curse? A narrative review of the risk of chlorhexidine resistance and the implications for infection prevention and control.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2022
    Review
  4. Article
  5. Article
  6. Assessing the Potential for Unintended Microbial Consequences of Routine Chlorhexidine Bathing for Prevention of Healthcare-associated Infections.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Sequential evolution of virulence and resistance during clonal spread of community-acquired methicillin-resistantProceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ryan C JohnsonDepartment of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.
Carey D SchlettInfectious Diseases Clinical Research Program, Department of Preventive Medicine and Biometrics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.
Katrina CrawfordInfectious Diseases Clinical Research Program, Department of Preventive Medicine and Biometrics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.
Jeffrey B LanierMartin Army Community Hospital, Fort Benning, Georgia, USA.
D Scott MerrellDepartment of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA douglas.merrell@usuhs.edu Michael.ellis606@gmail.com.
Michael W EllisDepartment of Medicine, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA douglas.merrell@usuhs.edu Michael.ellis606@gmail.com.
Uniformed Services University of the Health Sciences · USCommunity Hospital · US

Funding

DATA CENTER FOR EPIDEMIOLOGIC INVESTIGATIONS OF HIVN01AI005072 · NIAID · NEW ENGLAND RESEARCH INSTITUTES, INC. · PI MCKINLAY, SONJA M · 1990 to 1994
–
NIAID NIH HHS Y01 AI005072
6 · The paper itself

Abstract

We describe the selection of reduced chlorhexidine susceptibility during chlorhexidine use in a patient with two episodes of cutaneous USA300 methicillin-resistant Staphylococcus aureus abscess. The second clinical isolate harbors a novel plasmid that encodes the QacA efflux pump. Greater use of chlorhexidine for disease prevention warrants surveillance for resistance.

Indexed as

AbscessAdolescentBacterial ProteinsChlorhexidineDisinfectantsDrug Resistance, BacterialHumansMaleMembrane Transport ProteinsMethicillin-Resistant Staphylococcus aureusMicrobial Sensitivity TestsMilitary PersonnelMolecular Sequence DataPlasmidsRecurrenceSelection, GeneticBacterial ProteinsChlorhexidineDisinfectantsMembrane Transport ProteinsqacA protein, Staphylococcus aureus

Identifiers

PMID26292295
PMCPMC4609685
OpenAlexW2269956518

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.