Evidence map›Paper›PMID 26292222›Full record

SynthesisBrazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica2015

Cocos nucifera (L.) (Arecaceae): A phytochemical and pharmacological review.

E B C Lima, C N S Sousa, L N Meneses, N C Ximenes, M A Santos Júnior, G S Vasconcelos, N B C Lima, M C A Patrocínio, D Macedo, S M M Vasconcelos

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 284 citations in OpenAlex.

  1. Glutamate metabolic correlation analysis revealsFood chemistry. Molecular sciences · 2026
    Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Phytochemical profiling ofRSC advances · 2024
    Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

E B C LimaLaboratório de Neuropsicofarmacologia, Departamento de Fisiologia e Farmacologia, Faculdade de Medicina, Universidade Federal do Ceará, Fortaleza, CE, Brasil.
C N S SousaLaboratório de Neuropsicofarmacologia, Departamento de Fisiologia e Farmacologia, Faculdade de Medicina, Universidade Federal do Ceará, Fortaleza, CE, Brasil.
L N MenesesLaboratório de Neuropsicofarmacologia, Departamento de Fisiologia e Farmacologia, Faculdade de Medicina, Universidade Federal do Ceará, Fortaleza, CE, Brasil.
N C XimenesLaboratório de Neuropsicofarmacologia, Departamento de Fisiologia e Farmacologia, Faculdade de Medicina, Universidade Federal do Ceará, Fortaleza, CE, Brasil.
M A Santos JúniorLaboratório de Neuropsicofarmacologia, Departamento de Fisiologia e Farmacologia, Faculdade de Medicina, Universidade Federal do Ceará, Fortaleza, CE, Brasil.
G S VasconcelosLaboratório de Neuropsicofarmacologia, Departamento de Fisiologia e Farmacologia, Faculdade de Medicina, Universidade Federal do Ceará, Fortaleza, CE, Brasil.
N B C LimaLaboratório de Farmacologia, Centro Universitário Christus, Fortaleza, CE, Brasil.
M C A PatrocínioLaboratório de Farmacologia, Centro Universitário Christus, Fortaleza, CE, Brasil.
D MacedoLaboratório de Neuropsicofarmacologia, Departamento de Fisiologia e Farmacologia, Faculdade de Medicina, Universidade Federal do Ceará, Fortaleza, CE, Brasil.
S M M VasconcelosLaboratório de Neuropsicofarmacologia, Departamento de Fisiologia e Farmacologia, Faculdade de Medicina, Universidade Federal do Ceará, Fortaleza, CE, Brasil.
Universidade Federal do Ceará · BRUnichristus · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cocos nucifera (L.) (Arecaceae) is commonly called the "coconut tree" and is the most naturally widespread fruit plant on Earth. Throughout history, humans have used medicinal plants therapeutically, and minerals, plants, and animals have traditionally been the main sources of drugs. The constituents of C. nucifera have some biological effects, such as antihelminthic, anti-inflammatory, antinociceptive, antioxidant, antifungal, antimicrobial, and antitumor activities. Our objective in the present study was to review the phytochemical profile, pharmacological activities, and toxicology of C. nucifera to guide future preclinical and clinical studies using this plant. This systematic review consisted of searches performed using scientific databases such as Scopus, Science Direct, PubMed, SciVerse, and Scientific Electronic Library Online. Some uses of the plant were partially confirmed by previous studies demonstrating analgesic, antiarthritic, antibacterial, antipyretic, antihelminthic, antidiarrheal, and hypoglycemic activities. In addition, other properties such as antihypertensive, anti-inflammatory, antimicrobial, antioxidant, cardioprotective, antiseizure, cytotoxicity, hepatoprotective, vasodilation, nephroprotective, and anti-osteoporosis effects were also reported. Because each part of C. nucifera has different constituents, the pharmacological effects of the plant vary according to the part of the plant evaluated.

Indexed as

PhytotherapyAnalgesicsAnimalsAnticonvulsantsAntihypertensive AgentsAnti-Infective AgentsAnti-Inflammatory AgentsBone and BonesCocosHumansHypoglycemic AgentsPlant ExtractsProtective AgentsAnalgesicsAnticonvulsantsAntihypertensive AgentsAnti-Infective AgentsAnti-Inflammatory AgentsHypoglycemic AgentsPlant ExtractsProtective Agents

Identifiers

PMID26292222
PMCPMC4671521
OpenAlexW1797711379

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.