Evidence map›Paper›PMID 26292154›Full record

ArticlemAbs2015

Antibody-drug conjugates: Intellectual property considerations.

Ulrich Storz

Abstract read
In one paragraph

Article in mAbs, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Enriching cancer pharmacology with drugs of marine origin.British journal of pharmacology · 2020
    Review
  5. Review
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Ulrich Storza Michalski Hüttermann Patent Attorneys ; Düsseldorf , Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antibody-drug conjugates are highly complex entities that combine an antibody, a linker and a toxin. This complexity makes them demanding both technically and from a regulatory point of view, and difficult to deal with in their patent aspects. This article discusses different issues of patent protection and freedom to operate with regard to this promising new class of drugs.

Indexed as

Drug ApprovalIntellectual PropertyAdo-Trastuzumab EmtansineAminoglycosidesAntibodies, MonoclonalAntibodies, Monoclonal, HumanizedAntineoplastic AgentsBrentuximab VedotinGemtuzumabHumansImmunoconjugatesMaytansinePatents as TopicTrastuzumabUnited StatesUnited States Food and Drug AdministrationAdo-Trastuzumab EmtansineAminoglycosidesAntibodies, MonoclonalAntibodies, Monoclonal, HumanizedAntineoplastic AgentsBrentuximab VedotinGemtuzumabImmunoconjugatesMaytansineTrastuzumabADCantibodyantibody-drug conjugatesfreedom to operateimmunotoxinKadcylapatent

Identifiers

PMID26292154
PMCPMC4966491

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.