ArticlePLoS neglected tropical diseases2015
Bacillus anthracis Diversity and Geographic Potential across Nigeria, Cameroon and Chad: Further Support of a Novel West African Lineage.
Article in PLoS neglected tropical diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 23 papers.
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23 citing papers in PubMed, 37 citations in OpenAlex.
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- Molecular characterization of an outbreak-involved Bacillus anthracis strain confirms the spillover of anthrax from West Africa.Infectious diseases of poverty · 2024Article
- Beyond the spore, the exosporium sugar anthrose impacts vegetative Bacillus anthracis gene regulation in cis and trans.Scientific reports · 2023Article
- The potential distribution of Bacillus anthracis suitability across Uganda using INLA.Scientific reports · 2022Article
- Spatiotemporal Patterns of Anthrax, Vietnam, 1990-2015.Emerging infectious diseases · 2022Article
- Modelling the ecological niche of naturally occurring anthrax at global and circumpolar extents using an ensemble modelling framework.Transboundary and emerging diseases · 2022Article
- Seasonality and Ecological Suitability Modelling for Anthrax (Animals : an open access journal from MDPI · 2022Article
- No hints for abundance of Bacillus anthracis and Burkholderia pseudomallei in 100 environmental samples from Cameroon.European journal of microbiology & immunology · 2021Article
- Modeling the Potential Future Distribution of Anthrax Outbreaks under Multiple Climate Change Scenarios for Kenya.International journal of environmental research and public health · 2021Article
- TaqMan Assays for Simultaneous Detection ofPathogens (Basel, Switzerland) · 2020Article
- Convergent evolution of diverse Bacillus anthracis outbreak strains toward altered surface oligosaccharides that modulate anthrax pathogenesis.PLoS biology · 2020Article
- Potential distributions of Bacillus anthracis and Bacillus cereus biovar anthracis causing anthrax in Africa.PLoS neglected tropical diseases · 2020Article
- Predicting the Geographic Distribution of theThe American journal of tropical medicine and hygiene · 2020Article
- Nucleotide polymorphism assay for the identification of west African group Bacillus anthracis: a lineage lacking anthrose.BMC microbiology · 2020Article
- The global distribution of Bacillus anthracis and associated anthrax risk to humans, livestock and wildlife.Nature microbiology · 2019Article
- A case of Anthrax in two captive pumas (Puma concolor).The Journal of veterinary medical science · 2018Article
- Article
- Modeling the environmental suitability of anthrax in Ghana and estimating populations at risk: Implications for vaccination and control.PLoS neglected tropical diseases · 2017Article
- Role of Food Insecurity in Outbreak of Anthrax Infections among Humans and Hippopotamuses Living in a Game Reserve Area, Rural Zambia.Emerging infectious diseases · 2017Article
Corrections and comments
- Erratum issuedCorrection: Bacillus anthracis Diversity and Geographic Potential across Nigeria, Cameroon and Chad: Further Support of a Novel West African Lineage.2015 · Perrenten, Vincent [corrected to Perreten, Vincent]
Authors and funding
10 authors at 6 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Zoonoses, diseases affecting both humans and animals, can exert tremendous pressures on human and veterinary health systems, particularly in resource limited countries. Anthrax is one such zoonosis of concern and is a disease requiring greater public health attention in Nigeria. Here we describe the genetic diversity of Bacillus anthracis in Nigeria and compare it to Chad, Cameroon and a broader global dataset based on the multiple locus variable number tandem repeat (MLVA-25) genetic typing system. Nigerian B. anthracis isolates had identical MLVA genotypes and could only be resolved by measuring highly mutable single nucleotide repeats (SNRs). The Nigerian MLVA genotype was identical or highly genetically similar to those in the neighboring countries, confirming the strains belong to this unique West African lineage. Interestingly, sequence data from a Nigerian isolate shares the anthrose deficient genotypes previously described for strains in this region, which may be associated with vaccine evasion. Strains in this study were isolated over six decades, indicating a high level of temporal strain stability regionally. Ecological niche models were used to predict the geographic distribution of the pathogen for all three countries. We describe a west-east habitat corridor through northern Nigeria extending into Chad and Cameroon. Ecological niche models and genetic results show B. anthracis to be ecologically established in Nigeria. These findings expand our understanding of the global B. anthracis population structure and can guide regional anthrax surveillance and control planning.
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