ArticlePloS one2015
Changes in Inner and Outer Retinal Layer Thicknesses after Vitrectomy for Idiopathic Macular Hole: Implications for Visual Prognosis.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- The impact of extent of internal limiting membrane peeling on anatomical outcomes of macular hole surgery: results of a 54-week randomized clinical trial.Acta ophthalmologica · 2019Trial
- Polarimetric entropy mapping of retinal pigment epithelium in full-thickness macular hole by polarization-sensitive OCT.BMC ophthalmology · 2026Article
- Ganglion cell layer changes following the idiopathic macular hole surgery using inverted limiting membrane flap technique.BMC ophthalmology · 2025Article
- Retinal displacement and intraretinal structural changes after idiopathic macular hole surgery.Japanese journal of ophthalmology · 2022Article
- Correlations between Visual Performance and Chorioretinal Variables after Vitrectomy for the Idiopathic Macular Hole.Journal of ophthalmology · 2022Article
- Morphological and Functional Features in Patients with Idiopathic Macular Hole Treatment.International journal of general medicine · 2022Article
- Changes in each retinal layer and ellipsoid zone recovery after full-thickness macular hole surgery.Scientific reports · 2021Article
- Macular ganglion cell complex thickness after vitrectomy with the inverted flap technique for idiopathic macular holes.Arquivos brasileiros de oftalmologia · 2021Article
- Inner Retinal Layer and Outer Retinal Layer Findings after Macular Hole Surgery Assessed by means of Optical Coherence Tomography.Journal of ophthalmology · 2019Review
- Optical coherence tomography angiography features in patients with idiopathic full-thickness macular hole, before and after surgical treatment.Clinical interventions in aging · 2019Article
- Characteristics of retinal vessels in surgically closed macular hole: an optical coherence tomography angiography study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2017Article
- Evaluation of Ganglion Cell-Inner Plexiform Layer Thickness after Vitreoretinal Surgery with Internal Limiting Membrane Peeling in Cases with Idiopathic Macular Hole.Turkish journal of ophthalmology · 2017Article
- Preoperative and postoperative features of macular holes on en face imaging and optical coherence tomography angiography.American journal of ophthalmology case reports · 2017Article
- The Distribution of the Photoreceptor Outer Segment Length in a Healthy Population.Journal of ophthalmology · 2017Article
- Clinical and histological evaluation of large macular hole surgery using the inverted internal limiting membrane flap technique.Clinical ophthalmology (Auckland, N.Z.) · 2017Article
- Correlation between outer retinal layer thickness and cone density in patients with resolved central serous chorioretinopathy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2016Article
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8 authors.
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Abstract
purposeTo investigate sequential post-operative thickness changes in inner and outer retinal layers in eyes with an idiopathic macular hole (MH).
methodsRetrospective case series. Twenty-four eyes of 23 patients who had received pars plana vitrectomy (PPV) for the closure of MH were included in the study. Spectral domain optical coherence tomography C-scan was used to automatically measure the mean thickness of the inner and outer retinal layers pre-operatively and up to 6 months following surgery. The photoreceptor outer segment (PROS) length was measured manually and was used to assess its relationship with best-corrected visual acuity (BCVA).
resultsCompared with the pre-operative thickness, the inner layers significantly thinned during follow-up (P = 0.02), particularly in the parafoveal (P = 0.01), but not perifoveal, area. The post-operative inner layer thinning ranged from the ganglion cell layer to the inner plexiform layer (P = 0.002), whereas the nerve fiber layer was unaltered. Outer layer thickness was significantly greater post-operatively (P = 0.002), and especially the PROS lengthened not only in the fovea but also in the parafovea (P < 0.001). Six months after surgery, BCVA was significantly correlated exclusively with the elongated foveal PROS (R = 0.42, P = 0.03), but not with any of the other thickness parameters examined.
conclusionsFollowing PPV for MH, retinal inner layers other than the nerve fiber layer thinned, suggestive of subclinical thickening in the inner layers where no cyst was evident pre-operatively. In contrast, retinal outer layer thickness significantly increased, potentially as a result of PROS elongation linking tightly with favorable visual prognosis in MH eyes.
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