Evidence map›Paper›PMID 26290883›Full record

ArticleEGEMS (Washington, DC)2015

Development of an Algorithm to Classify Colonoscopy Indication from Coded Health Care Data.

Kenneth F Adams, Eric A Johnson, Jessica Chubak, Aruna Kamineni, Chyke A Doubeni, Diana S M Buist, Andrew E Williams, Sheila Weinmann, V Paul Doria-Rose, Carolyn M Rutter

Open access · diamondAbstract read
In one paragraph

Article in EGEMS (Washington, DC), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

  1. The Impact and Interactions of Race and Gender on Healthcare Use and Spending in Irritable Bowel Syndrome.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2025
    Article
  2. Article
  3. Risk for Post-Colonoscopy Irritable Bowel Syndrome in Patients With and Without Antibiotic Exposure: A Retrospective Cohort Study.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2022
    Article
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  12. Patterns of colorectal cancer screening uptake in newly eligible men and women.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Kenneth F AdamsMinnesota Department of Health.
Eric A JohnsonGroup Health Research Institute.
Jessica ChubakGroup Health Research Institute.
Aruna KamineniGroup Health Research Institute.
Chyke A DoubeniPerelman School of Medicine, University of Pennsylvania.
Diana S M BuistGroup Health Research Institute.
Andrew E WilliamsMaine Medical Center.
Sheila WeinmannKaiser Permanente Northwest.
V Paul Doria-RoseNational Cancer Institute.
Carolyn M RutterGroup Health Research Institute ; Rand Corp.
Kaiser Permanente Washington Health Research Institute · USKaiser Permanente · USMaine Medical Center · USMinnesota Department of Health · USNational Institutes of Health · USUniversity of Pennsylvania · US

Funding

The HMO Cancer Research Network (CRN)U19CA079689 · NCI · KAISER FOUNDATION HEALTH PLAN OF WASHINGTON · PI WAGNER, EDWARD H · 1999 to 2011
$62.6M
Studying Colorectal Cancer Effectiveness of Screening Strategies (SuCCESS)U54CA163261 · NCI · KAISER FOUNDATION RESEARCH INSTITUTE · PI CHUBAK, JESSICA · 2011 to 2017
$7.3M
SEARCH: Cancer Screening Effectiveness and Research in Community-based HealthcareUC2CA148576 · NCI · KAISER FOUNDATION HEALTH PLAN OF WASHINGTON · PI BUIST, DIANA SM, DOUBENI, CHYKE ABADAMA · 2010 to 2010
$2.0M
Improving Risk Stratification for Colonoscopy ScreeningR03CA171836 · NCI · MINNESOTA STATE DEPT OF HEALTH · PI ADAMS, KENNETH F. · 2013 to 2014
$149k
NCI NIH HHS R03 CA171836NCI NIH HHS U19 CA079689NCI NIH HHS U54 CA163261NCI NIH HHS UC2 CA148576
6 · The paper itself

Abstract

introductionElectronic health data are potentially valuable resources for evaluating colonoscopy screening utilization and effectiveness. The ability to distinguish screening colonoscopies from exams performed for other purposes is critical for research that examines factors related to screening uptake and adherence, and the impact of screening on patient outcomes, but distinguishing between these indications in secondary health data proves challenging. The objective of this study is to develop a new and more accurate algorithm for identification of screening colonoscopies using electronic health data.

methodsData from a case-control study of colorectal cancer with adjudicated colonoscopy indication was used to develop logistic regression-based algorithms. The proposed algorithms predict the probability that a colonoscopy was indicated for screening, with variables selected for inclusion in the models using the Least Absolute Shrinkage and Selection Operator (LASSO).

resultsThe algorithms had excellent classification accuracy in internal validation. The primary, restricted model had AUC= 0.94, sensitivity=0.91, and specificity=0.82. The secondary, extended model had AUC=0.96, sensitivity=0.88, and specificity=0.90. DISCUSSION: The LASSO approach enabled estimation of parsimonious algorithms that identified screening colonoscopies with high accuracy in our study population. External validation is needed to replicate these results and to explore the performance of these algorithms in other settings.

Indexed as

classificationcohort identificationcolonoscopydata use and qualityhealth information technologyLASSOROCscreening

Identifiers

PMID26290883
PMCPMC4537082
OpenAlexW2120139193

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.