Evidence map›Paper›PMID 26290770›Full record

ArticleJournal of environmental protection2012

Using Chemical Release Surveillance Data to Evaluate the Public Health Impacts of Chlorine and Its Alternatives.

Perri Zeitz Ruckart, Ayana Anderson, Wanda Lizak Welles

Abstract read
In one paragraph

Article in Journal of environmental protection, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

3 authors.

Perri Zeitz RuckartAgency for Toxic Substances and Disease Registry, Division of Toxicology and Human Health Sciences, Atlanta, GA, USA.
Ayana AndersonAgency for Toxic Substances and Disease Registry, Division of Toxicology and Human Health Sciences, Atlanta, GA, USA.
Wanda Lizak WellesNew York State Department of Health, Bureau of Toxic Substance Assessment, Albany, NY, USA.

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

backgroundMore than 80 million Americans may be at risk of a chemical exposure because they live near one of the 101 most hazardous chemical facilities or near routes used to transport hazardous chemicals. One approach to hazard reduction is to use less toxic alternatives. Chlorine, one of the chemicals posing the greatest public health danger, has several alternatives depending on the application.

methodsWe analyzed data collected during 1993-2008 by 17 state health departments participating in the Agency for Toxic Substances and Disease Registry's (ATSDR) active chemical incident surveillance program. We conducted descriptive analyses to evaluate whether five chlorine alternatives (calcium hypochlorite, hydrogen peroxide, sodium chlorate, sodium hydrosulfite, and sodium hypochlorite) resulted in less severe incidents. We used chi square and z-score analyses to test significance, where appropriate.

resultsDuring 1993-2008, 2040 incidents involved chlorine, and 1246 incidents involved chlorine alternatives. Nearly 30% of chlorine releases resulted in injured persons, as compared to 13% of chlorine alternatives that resulted in injury. Although similar proportions of persons injured in chlorine or chlorine alternative releases were treated on scene (18% and 14%, respectively) and at a hospital (58% and 60%, respectively), there was a greater proportion of hospital admissions following chlorine releases than there was following releases of chlorine alternatives (10 % vs. 4%) (p < 0.01). There were significantly fewer victims per release for hydrogen peroxide (0.2) than there were for chlorine (1.3) in paper manufacturing (p < 0.01).

conclusionExposures to these five potential chlorine alternatives resulted in a lower proportion of exposed persons requiring hospital admission. To reduce acute public health injuries associated with chemical exposures, users should consider a chlorine alternative when such a substitution is reasonable.

Indexed as

AlternativesChemicalsChlorineSubstitution

Identifiers

PMID26290770
PMCPMC4539300

What OpenQuestion holds

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