ReviewWorld journal of gastroenterology2015
Epigenetic regulation of DNA repair machinery in Helicobacter pylori-induced gastric carcinogenesis.
Review in World journal of gastroenterology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 23 citations in OpenAlex.
- Chemoradiotherapy Is Associated With Improved Overall Survival in Intestinal-Type Gastric Cancer: A Retrospective Analysis.World journal of oncology · 2026Article
- Rethinking Oxidative Stress inLife (Basel, Switzerland) · 2026Review
- Update on molecular pathogenesis ofWorld journal of gastrointestinal pathophysiology · 2025Review
- The pathogen's playbook in cancer: from oncogenesis to progression.Frontiers in oncology · 2025Review
- Increased ONECUT2 induced by Helicobacter pylori promotes gastric cancer cell stemness via an AKT-related pathway.Cell death & disease · 2024Article
- Review
- Pulmonary Pathogen-Induced Epigenetic Modifications.Epigenomes · 2023Review
- H. pylori infection alters repair of DNA double-strand breaks via SNHG17.The Journal of clinical investigation · 2020Article
- Prospects of NSAIDs administration as double-edged agents against endometrial cancer and pathological species of the uterine microbiome.Cancer biology & therapy · 2020Review
- From Gene to Protein-How Bacterial Virulence Factors Manipulate Host Gene Expression During Infection.International journal of molecular sciences · 2020Review
- Molecular Mechanisms Contributing Bacterial Infections to the Incidence of Various Types of Cancer.Mediators of inflammation · 2020Review
- Inhibition of G9a promoted 5-fluorouracil (5-FU) induced gastric cancer cell apoptosisRSC advances · 2019Article
- Molecular biology as a tool for the treatment of cancer.Clinical and experimental medicine · 2018Review
- New insights ofWorld journal of clinical cases · 2018Review
- How does bacterial pathogen Helicobacter pylori control responses to cellular stress?Future microbiology · 2017Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although thousands of DNA damaging events occur in each cell every day, efficient DNA repair pathways have evolved to counteract them. The DNA repair machinery plays a key role in maintaining genomic stability by avoiding the maintenance of mutations. The DNA repair enzymes continuously monitor the chromosomes to correct any damage that is caused by exogenous and endogenous mutagens. If DNA damage in proliferating cells is not repaired because of an inadequate expression of DNA repair genes, it might increase the risk of cancer. In addition to mutations, which can be either inherited or somatically acquired, epigenetic silencing of DNA repair genes has been associated with carcinogenesis. Gastric cancer represents the second highest cause of cancer mortality worldwide. The disease develops from the accumulation of several genetic and epigenetic changes during the lifetime. Among the risk factors, Helicobacter pylori (H. pylori) infection is considered the main driving factor to gastric cancer development. Thus, in this review, we summarize the current knowledge of the role of H. pylori infection on the epigenetic regulation of DNA repair machinery in gastric carcinogenesis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.