Evidence map›Paper›PMID 26290627›Full record

ReviewWorld journal of gastroenterology2015

Signs and genetics of rare cancer syndromes with gastroenterological features.

William Bruno, Giuseppe Fornarini, Paola Ghiorzo

Open access · bronzeAbstract readEditorialReview
In one paragraph

Review in World journal of gastroenterology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

William BrunoWilliam Bruno, Paola Ghiorzo, Genetics of Rare Cancers, Department of Internal Medicine and Medical Specialties, University of Genoa, IRCCS AOU San Martino-IST, 16132 Genoa, Italy.
Giuseppe FornariniWilliam Bruno, Paola Ghiorzo, Genetics of Rare Cancers, Department of Internal Medicine and Medical Specialties, University of Genoa, IRCCS AOU San Martino-IST, 16132 Genoa, Italy.
Paola GhiorzoWilliam Bruno, Paola Ghiorzo, Genetics of Rare Cancers, Department of Internal Medicine and Medical Specialties, University of Genoa, IRCCS AOU San Martino-IST, 16132 Genoa, Italy.
Ospedale Policlinico San Martino · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although the genetic bases of most hereditary cancer syndromes are known, and genetic tests are available for them, the incidence of the most rare of these syndromes is likely underestimated, partially because the clinical expression is neither fully understood nor easily diagnosed due to the variable and complex expressivity. The clinical features of a small pool of rare cancer syndromes include gastroenterological signs, though not necessarily tumors, that could require the intervention of a gastroenterologist during any of the phases of the clinical management. Herein we will attempt to spread the knowledge on these rare syndromes by summarizing the phenotype and genetic basis, and revising the peculiar gastroenterological signs whose underlying role in these rare hereditary cancer syndromes is often neglected. Close collaboration between geneticists and gastroenterologists could facilitate both the early identification of patients or relatives at-risk and the planning of multidisciplinary and tailored management of these subjects.

Indexed as

Biomarkers, TumorGastrointestinal DiseasesGenetic Predisposition to DiseaseGenetic TestingHeredityHumansNeoplastic Syndromes, HereditaryPhenotypePredictive Value of TestsPrognosisBiomarkers, TumorDiagnostic criteriaGastroenterological featuresGenetic susceptibilityGenetic testingRare cancer syndromes

Identifiers

PMID26290627
PMCPMC4533032
OpenAlexW1250220360

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.