Evidence map›Paper›PMID 26290579›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2015

Defusing redox bombs?

Nicholas F Polizzi, Agostino Migliore, Michael J Therien, David N Beratan

Abstract readComment
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Redox robustness drives LPMO evolution.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Tryptophan to Tryptophan Hole Hopping in an Azurin Construct.The journal of physical chemistry. B · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Oxalate decarboxylase uses electron hole hopping for catalysis.The Journal of biological chemistry · 2021
    Article
  12. Photoinduced hole hopping through tryptophans in proteins.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  13. Article
  14. Hole Hopping through Cytochrome P450.The journal of physical chemistry. B · 2020
    Article
  15. Mapping hole hopping escape routes in proteins.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  16. Article
  17. Why Are DNA and Protein Electron Transfer So Different?Annual review of physical chemistry · 2019
    Review
  18. Article
  19. Living with Oxygen.Accounts of chemical research · 2018
    Article
  20. Mean First-Passage Times in Biology.Israel journal of chemistry · 2016
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Nicholas F PolizziDepartment of Biochemistry, Duke University, Durham, NC 27708;
Agostino MiglioreDepartment of Chemistry, Duke University, Durham, NC 27708;
Michael J TherienDepartment of Chemistry, Duke University, Durham, NC 27708;
David N BeratanDepartment of Biochemistry, Duke University, Durham, NC 27708; Department of Chemistry, Duke University, Durham, NC 27708; Department of Physics, Duke University, Durham, NC 27708 david.beratan@duke.edu.

Funding

MAPPING OF ELECTRON TUNNELING PATHWAYS IN PROTEINSR01GM048043 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DAVID BERATAN · 1993 to 2026
$6.0M
Charge-Transfer Dynamics Relevant to Protein-Mediated Energy TransductionR01GM071628 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI THERIEN, MICHAEL J · 2004 to 2014
$2.3M
NIGMS NIH HHS GM-48043NIGMS NIH HHS GM-71628NIGMS NIH HHS R01 GM048043NIGMS NIH HHS R01 GM071628
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Oxidative StressHumansProteinsTryptophanTyrosineProteinsTryptophanTyrosine

Identifiers

PMID26290579
PMCPMC4568230

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.