ReviewFrontiers of medicine2015
Environmental pollution and DNA methylation: carcinogenesis, clinical significance, and practical applications.
Review in Frontiers of medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- Does air pollution play a role in infertility?: a systematic review.Environmental health : a global access science source · 2017Pooled it
- Pollution, Inflammation, and Vaccines: A Complex Crosstalk.International journal of environmental research and public health · 2021Review
- Polycyclic Aromatic Hydrocarbon Levels in Wistar Rats Exposed to Ambient Air of Port Harcourt, Nigeria: An Indicator for Tissue Toxicity.International journal of environmental research and public health · 2021Article
- Environment, Lifestyle, and Female Infertility.Reproductive sciences (Thousand Oaks, Calif.) · 2021Review
- Colorectal cancer patients withAging · 2020Article
- Particulate matter exposure shapes DNA methylation through the lifespan.Clinical epigenetics · 2019Review
- DNA methylation and exposure to ambient air pollution in two prospective cohorts.Environment international · 2017Article
- The epigenetic landscape of age-related diseases: the geroscience perspective.Biogerontology · 2017Review
- Defining, distinguishing and detecting the contribution of heterogeneous methylation to cancer heterogeneity.Seminars in cell & developmental biology · 2017Review
- Air pollution and DNA methylation alterations in lung cancer: A systematic and comparative study.Oncotarget · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Environmental pollution is one of the main causes of human cancer. Exposures to environmental carcinogens result in genetic and epigenetic alterations which induce cell transformation. Epigenetic changes caused by environmental pollution play important roles in the development and progression of environmental pollution-related cancers. Studies on DNA methylation are among the earliest and most conducted epigenetic research linked to cancer. In this review, the roles of DNA methylation in carcinogenesis and their significance in clinical medicine were summarized, and the effects of environmental pollutants, particularly air pollutants, on DNA methylation were introduced. Furthermore, prospective applications of DNA methylation to environmental pollution detection and cancer prevention were discussed.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.