Evidence map›Paper›PMID 26290128›Full record

ArticleThe Journal of veterinary medical science2016

Evaluation of two commercial PRRSV antibody ELISA kits with samples of known status and singleton reactors.

Byoung-Joo Seo, Hyunil Kim, Ho-Seong Cho, Byoung-Yong Park, Won-Il Kim

Abstract readEvaluation Study
In one paragraph

Article in The Journal of veterinary medical science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Byoung-Joo SeoCollege of Veterinary Medicine and Bio-Safety Research Institute, Chonbuk National University, Iksan, Korea.
Hyunil Kim
Ho-Seong Cho
Byoung-Yong Park
Won-Il Kim

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two commercial PRRSV ELISA kits (IDEXX and Bionote) were evaluated for their sensitivity and specificity using 476 PRRS-positive serum samples collected from 7 animal challenge experiments and 1,000 PRRS-negative sera. Both ELISA kits exhibited 100% sensitivity with sera collected 14 to 42 days post-infection, and the results from the kits were highly correlated (R(2)=0.9207). The specificity of IDEXX or Bionote kit was 99.9% or 99.7%, respectively. In addition, the Bionote ELISA kit was used to examine 100 sera that were determined to be falsely positive either by IDEXX 2XR or 3XR ELISA, and only 7 of these samples were found to be positive. These results indicate that both ELISA kits exhibited similar levels of sensitivity and specificity and would complement one another for the verification of false-positive samples.

Indexed as

Porcine respiratory and reproductive syndrome virusAnimalsAntibodies, ViralEnzyme-Linked Immunosorbent AssayPorcine Reproductive and Respiratory SyndromeReagent Kits, DiagnosticSensitivity and SpecificitySwineAntibodies, ViralReagent Kits, Diagnostic

Identifiers

PMID26290128
PMCPMC4751132

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.